Category: Disease Discoveries
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Investigating the Genetic Mechanisms Behind Uterine Fibroids
A recent Northwestern Medicine study has identified that a transcription factor protein called AP-1 regulates gene enhancers that may be responsible for promoting the development of uterine fibroids.
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New Coronavirus Protein Reveals Drug Target
A potential drug target has been identified in a newly mapped protein of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19).
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Gallbladder May Promote Transmission of Common Hospital-Acquired Infection
A recent study has found that the gallbladder may play a crucial role in the transmission of a common infection found in hospital settings, according to findings published in Nature Communications.
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Anti-Cancer Drug May Have Unintended Side Effects
An emerging strategy to boost fight cancer may actually harm certain immune cells, according to a recent study.
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Uncovering the Cellular Mechanisms Behind Genetic Mutations in ALS
Northwestern Medicine scientists have discovered that mutations in the largest genetic contributor to ALS leads to the dysfunction and eventual degeneration of certain specialized subtypes in the brain. The findings may lead to development of novel therapeutic interventions for the disease.
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Meat Consumption Raises Risk of Heart Disease and Death
A new study has linked the consumption of red and processed meat with a higher risk of heart disease and death.
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‘Cluster Bomb’ Toxin from Cholera Shuts Down Inflammatory Response While Attacking Cells
Northwestern scientists have determined that a toxin secreted by Vibrio cholerae bacteria, the pathogen responsible for cholera, suppresses the body’s normal immune response.
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Blood Pressure, Mobility and Cognition in Midlife
The cumulative effects of high blood pressure during young adulthood can affect gait and cognitive function during midlife, according to a recent study.
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New Migration of Brain Tumor Discovered
A previously unknown migration of glioblastoma may explain why current treatments stall out over time, according to a new study.
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Genetics Offers New Therapeutic Opportunities for Parkinson’s Disease
Northwestern Medicine scientists have recently discovered that two common genetic risk factors for Parkinson’s disease can be regulated with LRRK2 kinase inhibition or GCase enzyme activation, revealing potential for the development of new therapeutics.
