Category: Disease Discoveries
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New Inhibitor Starves HIV
An emerging cancer treatment also helps prevent cells from turning into viral factories by interfering with HIV infection processes inside the cell, according to a recent study.
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New Therapy Extends Breast Cancer Survival Rate, Prevents Reoccurrence
A new immunotherapy developed by investigators at Northwestern University dramatically extends the survival time of mice with triple negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.
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Chimeric Toxin Slows Cancer Growth
A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.
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Strategies for Evaluating Breast Cancer with Machine Learning
Machine-learning technology could help pathologists more accurately assess how a patient’s immune system is responding to breast cancer, according to a recent series of reports authored in part by Feinberg faculty.
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New Insights into Left Ventricular Cardiomyopathy
Genetic mutations in desmoplakin cause left ventricular cardiomyopathy, rather than right ventricular cardiomyopathy as previously believed, according to a recent study.
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Antibody Testing Project Receives NSF RAPID Grant
Northwestern investigators have received a $200,000 grant from the National Science Foundation to examine the determinants of SARS-CoV-2 exposure with a minimally invasive approach to community-based serological testing.
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New Mechanism for Oncogenic Gene Splicing
Northwestern Medicine scientists have discovered an alternate mechanism for aberrant gene splicing that contributes to T-cell lymphoblastic leukemia, according to a recent study.
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Study Reveals Molecular Mechanisms Behind Genetic Kidney Disease
A Northwestern Medicine study has uncovered the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD) and a potential drug target.
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Specialized Immune Cells May Improve Early Detection of Parkinson’s Disease
An elevated presence of specialized immune cells were found in patients prior to developing motor symptoms and receiving a diagnosis of Parkinson’s disease, which may help improve early detection.
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Cancer Cells Hijack Nucleotide Metabolism to Boost Cell Proliferation
Mutations in the genes RAS and RAF allow cancer cells to create their own nucleotides, fueling cancer growth, according to a recent study published in Molecular Cell.
