Category: Disease Discoveries
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Improving Interferon Therapy for Blood Cancers
Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications. Targeting this pathway in combination with interferon therapy may provide a novel approach to[…]
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Improving Interferon Therapy for Blood Cancers
Investigators have discovered a novel signaling pathway in interferons that suppresses their anti-tumor response in patients with a particular type of blood cancer.
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T-Cell Interactions Vary Between Tumor Microenvironments
A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within different parts of brain tumor and brain metastasis microenvironments.
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CRISPR and HIV: New Technique in Human Blood Unveils Potential Paths Toward Cure
New advances in CRISPR gene-editing technology may lead to longer-lasting treatments and new therapeutic strategies for HIV/AIDS.
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Lower Statin Threshold Shown to be Cost-Effective
Expanding prescription of statin medication to reduce low-density lipoprotein cholesterol could be a cost-effective intervention against cardiovascular disease, according to a recent study.
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Lymphatics Aid Heart Repair
Expression of a growth factor after heart injury activates the lymphatic system, spurring leukocytes to help clear away dying cells, according to a recent study.
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Can Weekly Prednisone Treat Obesity?
Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight.
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New Genetic Risk Factors for Arrhythmia Discovered
A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder.
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Investigators Identify Potential Therapeutic Target for Pancreatic Cancer
Investigators discovered that decreased expression of the G alpha 13 protein in mice and human pancreatic tumors promotes tumor growth, according to recent findings.
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Northwestern Investigates COVID-19: Antibodies, Global Surveillance, Women in Research
Northwestern Medicine continues to help advance the understanding of the COVID-19 pandemic and its widespread impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research to highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.
