The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.
Northwestern Medicine scientists have developed a novel testing platform to assess, in real time, the efficacy of nanomaterials in regulating gene expression.
According to a new study, normal agers lost volume in the cortex, which contains neurons, twice as fast as SuperAgers, a rare group of older people whose memories are as sharp as those decades younger.
A new review, published in Nature Reviews Neurology, outlines how upper motor neuron degeneration is an important feature in ALS pathology, and could be key to developing better diagnostic tools and treatments for ALS.
A Northwestern Medicine study uncovered novel findings about sodium channels in neurons that may represent a novel therapeutic target for epilepsy treatment.
Northwestern Medicine scientists and co-authors defined a role for the WAVE1 protein in the cellular mechanisms behind cocaine addiction.
When Major League Baseball players travel in a way that misaligns their internal 24-hour clock with the natural environment and its cycle of sunlight, they suffer negative consequences, according to a recent study.
A Northwestern Medicine study, led by a PhD student, found that overexpressing a protein called CREB improved memory impairments in aged rats.
Northwestern Medicine scientists have identified a link between Huntington’s disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.
Northwestern Medicine scientists have demonstrated an alternate method of signaling used by proteins called group I metabotropic glutamate receptors, a finding that could be used to develop novel drug treatments for many neurological disorders.