Tag: Research
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Mutation Provides Insights Into Mechanisms of Neurodegeneration in Parkinson’s Disease
A mutated protein expressed in lysosomes may contribute to Parkinson’s disease, according to a new Northwestern Medicine study published in the Journal of Cell Biology.
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Evaluating Outcomes of Extended Thrombolytic Therapy for Ischemic Stroke
Thrombolytic therapy administered longer after the onset of ischemic stroke than current recommendations did not demonstrate improved clinical outcomes as compared to placebo, according to a recent trial published in the New England Journal of Medicine.
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Shape-Shifting Ultrasound Stickers Detect Post-Surgical Complications
Investigators have developed a new, first-of-its-kind sticker that enables clinicians to monitor the health of patients’ organs and deep tissues with a simple ultrasound device.
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Release of Inhibitory Pathways May Promote Immune Response to HIV
Recent work from the laboratory of Elena Martinelli, PhD, MPH, has discovered how inhibiting an immune cell singling pathway in a model of HIV-1 infection may promote immune responses and decrease viral persistence in conjunction with antiretroviral therapy.
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Study Examines Delayed Pediatric Diagnoses in Emergency Departments
Emergency departments that see fewer pediatric patients are more likely to give delayed diagnoses for serious medical conditions compared to those who see pediatric patients more often, according to a Northwestern Medicine study published in JAMA Pediatrics.
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Innate Immune Cells Promote Growth of Blood Vessels in Colon Cancer
A type of white blood cell is responsible for growth and branching of blood vessels which supports tumor growth in colon cancer, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
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New Drug Shows Promise for Treating Rare Brain Tumors
An experimental drug may provide a new treatment option for some patients with rare incurable brain tumors, according to an analysis published in the Journal of Clinical Oncology.
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Treating Skin Cancer Without Risking Transplanted Kidneys in Organ Recipients
Specific immunosuppressants and immunotherapy are not enough to prevent organ rejection in patients undergoing skin cancer treatment who have also received a kidney transplant, according to a clinical trial published in the Journal of Clinical Oncology.
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Cellular Therapy Increases Survival in Recurring B-cell Lymphoma
A two-year follow-up clinical trial found that a personalized cellular therapy treatment for relapsed or refractory B-cell lymphoma demonstrated high safety and improved overall survival in patients, according to findings published in Blood.
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Outsmarting Chemo-Resistant Ovarian Cancer
Northwestern Medicine scientists have discovered the Achilles heel of chemotherapy-resistant ovarian cancer — its hunger for cholesterol — and how to sneakily use that to destroy it.
