Tag: Pediatrics
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Bariatric Surgery in Adolescents ‘Reprograms’ Kidney Biology to Promote Recovery
Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms that may serve as potential targets for non-surgical treatments for diabetic kidney disease, according to a multi-institutional study published in The Journal of Clinical Investigation.
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First Gene Regulation Clinical Trials for Epilepsy Show Promising Results
A first‑ever gene‑regulation therapy tested in early‑phase clinical trials co‑led by Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago has proven safe in children with Dravet syndrome who have exhausted conventional treatment options, according to a study published in the New England Journal of Medicine.
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AI Model Predicts Language Development in Children with Hearing Loss
An advanced machine learning model predicted spoken language outcomes in children who received cochlear implants more accurately than traditional machine learning approaches, according to a recent Northwestern Medicine-led international multi-center study.
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First-Of-Its-Kind Probe Monitors Fetal Health in Utero During Surgery
Northwestern University scientists have developed the first device that can continuously track a fetus’s vital signs while still in the uterus — a feat that previously has not been possible.
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Evaluating Treatment of Heart Defects in Preterm Infants
Early pharmacologic treatment of a common congenital heart defect did not improve survival outcomes compared to expectant management in preterm infants, according to a recent clinical trial published in JAMA.
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Experimental Drug Shows Promise for Rare Genetic Disorder
A new experimental therapy has shown encouraging results in treating a rare and progressive lysosomal storage disorder, according to findings from a multi-year clinical trial published in the New England Journal of Medicine.
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Preventing Lung Disease in Preterm Babies
A multicenter clinical trial found that intratracheal steroids do not reduce the risk of lung disease or death in extremely preterm infants, according to the study published in JAMA.
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Mapping How Children Receive Emergency Care in the U.S.
A Northwestern Medicine-led study has established the first pediatric-specific atlas of acute care regions across the United States, offering the clearest picture of how children access emergency and inpatient services to date, according to the study published in JAMA Pediatrics.
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Study Identifies Gene Linked to Rare Ciliopathy Disorders
A Northwestern Medicine-led study has identified mutations in the gene CEP76 as a new cause of ciliopathies, shedding light on a complex group of disorders that affect multiple body systems, according to a study published in Science Advances.
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AI Models Predict Sepsis in Children, May Enable Preemptive Care
Northwestern scientists have developed and validated AI models that accurately identify children at high risk for sepsis within 48 hours, so they can receive early preemptive care.
