Tag: Neuroscience
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Understanding the Link Between Genetic Risk and Brain Communication Disorders
A new Northwestern Medicine study suggests a major psychiatric risk gene remains important well into adulthood and may influence brain communication, according to a study published in the Proceedings of the National Academy of Sciences.
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Study Uncovers Potential Gene Therapy for Late-Stage Parkinson’s Side-Effects
Northwestern Medicine scientists have discovered that suppressing excitatory synaptic transmission in a small group of neurons in the brain may reverse levodopa-induced dyskinesia in patients with late-stage Parkinson’s disease without reducing the symptomatic benefits of levodopa treatment, according to a recent study published in Neuron.
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FDA-Approved Compound Promotes Neuroprotective Effects in Parkinson’s Disease
Northwestern Medicine scientists have discovered an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson’s disease, according to a recent study published in The Journal of Clinical Investigation.
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Targeting Aberrant Learning May Improve Parkinson’s Treatment
Northwestern Medicine scientists have discovered that targeting neuronal signaling controlling aberrant learning in the striatum may improve the efficacy of a first-line therapy for Parkinson’s disease and has the potential to reduce therapy-related side effects, according to a recent study published in Science Advances.
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A New Clue to ALS and FTD: Faulty Protein Disrupts Brain’s ‘Brake’ System
A new Northwestern study has uncovered how a key disease protein drives overactive nerve cells in neurodegenerative diseases like ALS and frontotemporal dementia.
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Identifying New Therapeutic Strategies for Psychiatric Disorders
A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson’s disease symptoms, according to findings published in Molecular Psychiatry.
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Northwestern Establishes New Center for Ataxia Research and Treatment
Northwestern has established the Denning Ataxia Center, a multidisciplinary hub dedicated to improving the understanding of ataxia through integrating leading-edge research with patient-centered clinical care, with the goal of unraveling the complexities of the condition and developing improved treatments.
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Non-Neuron Brain Cells Produce a Third of Amyloid Plaque in Alzheimer’s Disease
An international team of investigators have discovered that oligodendrocytes contribute approximately one-third of plaque formation alongside neurons in mouse models of Alzheimer’s disease, according to a recent study published in Nature Neuroscience.
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Investigating the Molecular Mechanisms of ‘Forgetting’
Northwestern Medicine investigators have uncovered a new way in which neurons in the brain “forget” associations that help guide behavior and habits, according to a study published in Cell Reports.
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Embryo’s Signaling Mechanism May Promote Healthy Aging, Combat Neurodegenerative Diseases
Northwestern investigators have identified a novel transcription factor which regulates a signaling mechanism utilized by a fertilized embryo to protect its mother from cellular and environmental stress, according to a recent study to published in the journal Genes and Development.
