Today, more than 50 million adults in the U.S. suffer from chronic pain — pain lasting longer than three months — and is the most common reason why people seek medical attention, according to the Centers for Disease Control and Prevention (CDC).
A new Northwestern University-led study published in Nature Neuroscience has discovered that dopamine neurons are more diverse than previously thought, opening new research directions for further understanding and potentially even treating Parkinson’s disease.
Scientists have discovered that antipsychotic drugs – which inhibit the overactive dopamine causing the symptoms of schizophrenia – interact with a completely different neuron than originally thought.
A Northwestern Medicine study has uncovered novel cellular mechanisms within the retina, findings that could help advance the development of targeted therapeutics for diseases and conditions impacting vision.
Investigators led by D. James Surmeier, PhD, the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington’s disease.
Northwestern Medicine investigators have discovered novel sex-specific mechanisms that control how stress hormones impact dopamine transmission and motivation, findings that can inform new therapeutic strategies for treating major depressive disorder.
A new study is the first to show that extrapolating physiological findings from small animals can produce incorrect predictions in humans.
Investigators have discovered novel neural mechanisms that influence sex differences in the motivation based on past experiences, according to findings published in Nature Neuroscience.
Targeting calcium signaling in neurons may represent a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study.
Feinberg has established the Center for Psychiatric Neuroscience, a collaborative hub created to unite interdisciplinary scientists to understand neural mechanisms underlying mental illness, elucidate mechanisms of psychotropic drug action and develop novel therapeutics.