Inter-organelle contacts drive calcium transfer from lysosomes to mitochondria, findings that lay out a possible therapeutic blueprint for neurological disorders.
Northwestern Medicine investigators have discovered that a specific protein known for its role in cell division also impacts the direction of intracellular transport in neurons.
Neurons in the olfactory cortex coordinate to boost the sense of smell when anticipating an odor, according to a Northwestern Medicine study.
African Americans who were exposed to segregation in their neighborhoods during young adulthood are more likely to have poor cognitive performance as early as midlife.
An elevated presence of specialized immune cells were found in patients prior to developing motor symptoms and receiving a diagnosis of Parkinson’s disease, which may help improve early detection.
Both the hippocampus and the orbitofrontal cortex are involved in inference-based behavior, according to a new study.
Small projections of dendritic spines known as spinules are unexpectedly dynamic, while a stable subgroup may form multi-synaptic spine connections, according to the first detailed study of their behavior.
Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.
A Northwestern Medicine study has identified looped neural connections between the cortex and thalamus, providing a new understanding of connectivity between the two brain regions.
Neural signaling that encodes certain memories as negative could impact anxiety and substance misuse disorders, according to a recent study.