Tag: Medicine
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Drug Shows Promise for Starving Out Cancer Cells
Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a study published in Science Advances.
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Targeting Protein Interactions May Boost Antitumor Immunity in Breast Cancer
A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses, according to findings published in the Journal of Clinical Investigation.
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Novel Mechanism Supports Antitumor Response and T-cell Survival
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
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Study Uncovers Novel Mechanisms Behind Food Allergies
A recent Northwestern Medicine study sheds light on the mechanisms of a specific protein that is necessary for the production of IgA antibodies in the gut in response to food allergens, according to findings published in the journal Mucosal Immunology.
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Release of Inhibitory Pathways May Promote Immune Response to HIV
Recent work from the laboratory of Elena Martinelli, PhD, MPH, has discovered how inhibiting an immune cell singling pathway in a model of HIV-1 infection may promote immune responses and decrease viral persistence in conjunction with antiretroviral therapy.
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Treating Skin Cancer Without Risking Transplanted Kidneys in Organ Recipients
Specific immunosuppressants and immunotherapy are not enough to prevent organ rejection in patients undergoing skin cancer treatment who have also received a kidney transplant, according to a clinical trial published in the Journal of Clinical Oncology.
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Cellular Therapy Increases Survival in Recurring B-cell Lymphoma
A two-year follow-up clinical trial found that a personalized cellular therapy treatment for relapsed or refractory B-cell lymphoma demonstrated high safety and improved overall survival in patients, according to findings published in Blood.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Transcription Factors Influence Insulin-Producing Beta Cells
A recent study from the laboratory of Joseph Bass, MD, PhD, has revealed how transcription factors within individual cells influence the identity and function of insulin-producing beta cells in the pancreas, according to findings published in Cell Metabolism.
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As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials
A lack of cancer progression could be used as a surrogate for overall survival in newly metastatic prostate cancer clinical trials, according to a new meta-analysis published in the Journal of Clinical Oncology.
