Tag: Medicine
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Transcription Factors Influence Insulin-Producing Beta Cells
A recent study from the laboratory of Joseph Bass, MD, PhD, has revealed how transcription factors within individual cells influence the identity and function of insulin-producing beta cells in the pancreas, according to findings published in Cell Metabolism.
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As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials
A lack of cancer progression could be used as a surrogate for overall survival in newly metastatic prostate cancer clinical trials, according to a new meta-analysis published in the Journal of Clinical Oncology.
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Novel Protein Interactions May Serve as Biomarker for Heart Disease
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
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Defining Rheumatoid Arthritis Subtypes May Improve Treatments
By profiling the inflammatory cells types in joint tissue biopsy samples, scientists have characterized six subtypes of rheumatoid arthritis, an approach that could help physicians tailor more effective treatment strategies for patients based on disease type, according to findings published in Nature.
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New Brain-Like Transistor Mimics Human Intelligence
Taking inspiration from the human brain, scientists have developed a new synaptic transistor capable of higher-level thinking, according to results published in the journal Nature.
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Semaglutide Trials Show Improvements in Cardiovascular Health, Quality of Life
Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.
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Drug Extends Survival in Prostate Cancer with Genetic Mutations
Men with hormone-resistant prostate cancer and specific genetic mutations who were treated with the drug olaparib survived longer than men treated with traditional hormone therapy, according to a post hoc analysis published in the Journal of Clinical Oncology.
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Understanding Healthcare Worker Collaboration and Patient Outcomes
Some interventions designed to improve healthcare worker collaboration may not improve patient outcomes, according to a recent trial published in the Annals of Internal Medicine.
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Novel Approaches for Correcting Gene Expression Insufficiency
A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by insufficient protein levels, according to a study published in Nature Communications.
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Pioneering Automated Proteoform Imaging
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
