Tag: Genetics
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Enzyme Blocker Stops Growth of Deadly Brain Tumor
Scientists discovered the regulatory role of the enzyme CDK5 in an aggressive form of brain cancer and successfully halted tumor growth by inhibiting it.
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Gene Therapy for Thalassemia Shows Promise
In new clinical trials, a gene therapy for a serious blood disorder called beta-thalassemia significantly improved outcomes among patients, without serious side effects.
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Genome Analysis Identifies Mutations in Pediatric Cancers
Scientists found more than 100 possible cancer-causing mutations and defective alleles in a large-scale genetic analysis of pediatric cancers that was co-authored by Elizabeth Perlman, MD, and published in Nature.
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Machines See the Future for Patients Diagnosed With Brain Tumors
Scientists have developed software that can forecast the survival of patients diagnosed with glioma that is more accurate than physicians’ predictions.
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The CRISPR Revolution
Northwestern Medicine scientists usher in a new era of genetic research. Learn how our investigators are using CRISPR technology to isolate mutations that cause neurological diseases and to understand how individual genes can damage or protect cells.
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Genetic Basis Uncovered for Glaucoma
Northwestern Medicine scientists have discovered mutations that cause improper drainage and a buildup of ocular pressure leading to glaucoma, suggesting a path towards future treatments.
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Breaking Ground in the Field of Personalized Neurology
A team from the academic and clinical arms of Northwestern Medicine has been assembled to study patient DNA and create customized therapies for Parkinson’s, Epilepsy, and ALS in a model called Personalized Neurology.
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Scientists Reprogram Stem Cells to Regenerate Muscle in Muscular Dystrophy
Scientists are one step closer to a stem cell treatment for muscular dystrophy after Northwestern Medicine investigators demonstrated improvements in muscle tissue differentiation in stem cells.
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Blocking Gene Expression Improves Outcomes in Blood Disease in Models
Scientists reduced blood clotting in mice with a blood disease called myeloproliferative neoplasm by inhibiting expression of a gene.
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Northwestern to Advance Our Understanding of the Role of Environment on Genes
A new $10 million gift from University trustees and supporters Louis A. Simpson ’58 and Kimberly K. Querrey will create a center to study the effects of environment on the activation and expression of genes.
