Tag: Cancer
-
Combination Treatment Extends Survival in Advanced Bladder Cancer
Immunotherapy administered before and after chemotherapy along with surgical removal of the bladder improved survival compared to chemotherapy alone in patients with muscle-invasive bladder cancer, according to a recent study published in the New England Journal of Medicine.
-
Molecular Profiling May Improve Meningioma Decisionmaking
Investigators have demonstrated how molecular profiling of tumors can be used to help predict treatment response and survival in patients with meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Medicine.
-
Combination Treatment Improves Progression-Free Survival in Advanced Prostate Cancer with Genetic Mutations
A combination therapy improved progression-free survival in patients with metastatic castration-resistant prostate cancer with genetic mutations compared to either therapy alone or sequentially, according to results from a Northwestern Medicine-led clinical trial.
-
Intercellular Mechanisms Regulate Gene Expression in Cancer Cells
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
-
Investigators Discover New Therapeutic Target for Pediatric Brain Cancers
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
-
Understanding Epigenetic Control of Antibody Responses
Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.
-
Study Finds Noncoding RNAs Dysregulated in Several Human Cancers
Northwestern Medicine scientists have discovered new insights into the production and regulation of an emerging class of noncoding RNAs in three major types of cancer, according to findings published in Science Advances.
-
Scientists Discover Potential Biomarker in Rare Skin Cancer
Northwestern Medicine scientists have discovered increased immune cell activity in Merkel cell carcinoma tumors, which could help predict treatment response in patients and inform the development of new targeted therapies, according to findings published in the journal Cancer Discovery.
-
Developing New Methods for Targeted Protein Degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology.
-
Exploring CAR T-cell Therapy for Aggressive Follicular Lymphoma
CAR T-cell therapy is an effective treatment for aggressive subtypes of follicular lymphoma, according to a clinical trial published in Nature Medicine.
