Leukemia Hijacks Nucleotide Metabolism
T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
Browsing: "Cancer"
Uncovering How Protein Complexes Impact Gene Expression
Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
Why Black Men’s Prostate Cancer May be More Responsive to Immunotherapy
A new Northwestern Medicine study has discovered why Black men die more often of prostate cancer yet also have greater survival benefits from immunotherapy treatments.
Study Identifies New Potential Therapeutic Approach for Glioblastoma
Northwestern Medicine investigators have identified a potential combined targeted therapy approach for treating glioblastoma, according to a recent study published in the journal Scientific Reports.
Improving Treatment for Triple-Negative Breast Cancer
A team led by Northwestern Medicine investigators has identified a novel molecular target that may improve the efficacy of current treatments for triple-negative breast cancer.
2020: A Year of Groundbreaking Discoveries During a Pandemic
Take a look back at a handful of groundbreaking research discoveries that marked one of, if not the most, unprecedented and transformative years for Feinberg.
Streamlining Chemical-Genetic Screening
Northwestern Medicine scientists have developed a new high-throughput sequencing tool to test how drugs interact with genetically modified cells.
Discovering New Mechanisms in Epigenetics
A series of recent discoveries by Northwestern Medicine scientists point to a more nuanced understanding of how epigenetic regulators function.
Identifying Oncogenes through Epigenetic Markers
Northwestern Medicine investigators have discovered that oncogenes contain specific epigenetic markers called broad genic repression domains, which could help identify potential therapeutic targets for cancer treatment.
Novel “Gate Latch” Mechanism Essential for Activation of Immune System
Northwestern Medicine investigators have identified a novel “gate latch” mechanism within the Orai1 ion channel that is essential for proper activation of the immune system.