Tag: Cancer
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Anti-Cancer Inhibitor Could Have Dual Effect
TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
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Lurie Cancer Center Receives Merit Extension from NCI
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a Merit Extension Award from the National Cancer Institute, one of only two Comprehensive Cancer Centers in the nation to earn the recognition.
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For Every Man: Northwestern Investigators’ Critical Impact on Prostate Cancer
From teasing out determinants of health disparities to developing precision medicine treatments, clinicians and scientists from the Lurie Cancer Center are dramatically changing the landscape for all men with prostate cancer.
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Study Identifies Expanded Role for Metabolic Enzyme in Kidney Cancer
The underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma, which accounts for 80 percent of all kidney cancers, according to a recent study.
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Advancing Treatment for B-cell Acute Lymphoblastic Leukemia
Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell immunotherapy, demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia, according to recent findings.
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Skin Cancer Harbors Targetable Mutation
An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
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Translational Science: Glioblastoma
Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.
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Improving Immune Response Against Viral Infections and Disease
Blocking an inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.
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Revising Theory of Cancer-Induced Immune Suppression
Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a Northwestern Medicine study.
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Some Chemotherapy Side Effects Could Be Prevented
Harmful side effects from a common chemotherapy drug could be prevented in patients with a specific mutation by targeting retinoic acid receptors, according to a recent study.
