Tag: Biochemistry
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Early- and Mid-Career Investigators Recognized by NIH
Two Northwestern Medicine scientists have received NIH Director’s Awards, which fund innovative research with high-impact potential.
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Unexpected Findings Uncover New Understanding of Gene Expression
Northwestern Medicine scientists have discovered surprising findings about an enzyme central to gene expression and mutated in many cancers.
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Toxic Genetic Material’s Origins Discovered
A Northwestern Medicine study found a novel chemical transformation in the formation of colibactin, a toxic agent produced by gut bacteria, including certain strains of E. Coli.
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Understanding Key Enzyme’s Role in Embryonic Development
A new Northwestern Medicine study reveals surprising findings about an enzyme called Set1A and its function in embryonic stem cell self-renewal and differentiation.
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Scientists Discover Key Cellular Mechanism Underlying Parkinson’s Disease
The major features of Parkinson’s disease have been linked to a toxic cascade beginning with oxidized dopamine, providing a possible therapeutic pathway.
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How Babies’ Environments Lead to Poor Health Later
Northwestern scientists have found that nutritional, microbial and psychosocial exposures early in infant development predict DNA methylation later in life.
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New Technology to Manipulate Cells Could One Day Help Treat Parkinson’s, Arthritis, Other Diseases
A synthetic material developed at Northwestern Medicine could direct a patient’s existing cells to transform into stem cells, creating a new treatment path for stem cell therapy.
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First Spherical Nucleic Acid Drug Injected into Humans Targets Brain Cancer
The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.
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Uncovering the Genetic Mechanisms Driving Embryonic Development
A new Northwestern Medicine study, published in Genes and Development, has identified two DNA elements crucial to the activation of a set of genes that drive the early development of embryos.
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Uncovering a Novel Mechanism in Cell Division
Northwestern Medicine scientists have demonstrated an important role for the methylation of the amino terminus of a specific protein in maintaining centromere function and chromosome segregation, both important in cell division.
