Tag: Biochemistry
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Disrupting Gene Transcription Elongation to Treat Cancer
Targeting cancer cells with a transcription elongation inhibitor delayed tumor progression in animal models, according to a recent Northwestern Medicine study.
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Prindle Receives 2018 Packard Fellowship
Arthur Prindle, PhD, assistant professor of Biochemistry and Molecular Genetics, will study bacterial communication and its potential applications to human health with a five-year grant from The David and Lucile Packard Foundation.
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New Bio-Inspired Dynamic Materials Transform Themselves
Scientists have developed soft materials that assemble and disassemble on demand, opening the door for applications including robotics, drug delivery and tissue regeneration.
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3-D Structure of COMPASS Protein Complex Revealed
The three-dimensional atomic structure of the epigenetic driver COMPASS was solved for the first time in a study published in the journal Cell.
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Shilatifard Named Editor of Science Advances
Ali Shilatifard, PhD, has been appointed editor of Science Advances, an open-access journal published by the American Association for the Advancement of Science, which also publishes the journal Science.
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Resetting the Epigenetic Balance for Cancer Therapy
Northwestern Medicine scientists have discovered an epigenetic imbalance that can lead to cancer, and used these findings to inhibit tumors in models.
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Scientists Reprogram Stem Cells to Regenerate Muscle in Muscular Dystrophy
Scientists are one step closer to a stem cell treatment for muscular dystrophy after Northwestern Medicine investigators demonstrated improvements in muscle tissue differentiation in stem cells.
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New Insights Into Protein Reveal Potential Therapy for Breast Cancer
Northwestern Medicine scientists have uncovered new findings about a protein called SET1B, which could offer a novel approach to treating triple-negative breast cancer.
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Discovering a Protein’s Role in Gene Expression
Northwestern Medicine scientists have discovered that a protein called BRWD2/PHIP binds to H3K4 methylation, a key molecular event that influences gene expression.
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Previously Unknown Gene Mutation May Increase Risk for Heart Disease
A newly discovered gene mutation may increase a patient’s risk of genetic heart disease, presenting a target for therapy or genetic screening down the road.
