Tag: Biochemistry and Molecular Genetics
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Localized Genetic Mutations May Serve as Biomarker for Wide Range of Cancers
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
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Pioneering Biochemist Craig Crews Named Winner of 2024 Kimberly Prize
Northwestern University Feinberg School of Medicine and the Simpson Querrey Institute for Epigenetics announced today that renowned biochemist Craig M. Crews, PhD, who pioneered the pharmaceutical field of targeted protein degradation, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
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New Human Gene Cluster Sequence Discovered
Investigators from the laboratory of Ali Shilatifard, PhD, have discovered a new repeat gene cluster sequence that is exclusively expressed in humans and non-human primates, according to findings published in Science Advances.
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Pioneering Automated Proteoform Imaging
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
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Exploring Transcription Elongation Control in Development, Disease and Aging
In a recent article published in Molecular Cell, the laboratory of Ali Shilatifard, PhD, provided a comprehensive overview of the current understanding of the elongation stage of DNA transcription and how its dysregulation is associated with developmental defects, disease and aging.
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Small, Implantable Device Could Sense and Treat Cancer
A multi-institutional team of investigators including Northwestern University scientists has received $45 million to fast-track the development of a first-of-its-kind implant to sense and treat cancer.
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Protein Controls Lymphoma Cell Metabolism, Promotes Cancer Growth
Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
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Engineered Probiotic Can ‘Sense’ Inflammatory Bowel Disease
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
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Novel Sequencing Tool Accelerates Analysis of Tumor Cells
Northwestern Medicine investigators led by Ruli Gao, PhD, have developed a novel genetic sequencing tool that accelerates sequencing analysis of same-cell genotypes and phenotypes in tumors, as detailed in a study published in Nature Communications.
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Chandel Receives 2023 Lurie Prize in Biomedical Sciences
Navdeep Chandel, PhD, the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care and of Biochemistry and Molecular Genetics, has been named a recipient of the 2023 Lurie Prize in Biomedical Sciences by the Foundation for the National Institutes of Health.
