Tag: Biochemistry and Molecular Genetics
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Shilatifard Elected to National Academy of Sciences
Ali Shilatifard, PhD, the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, has been elected to the National Academy of Sciences.
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Protein Implicated as Driver of Lung Cancer
Northwestern Medicine scientists have uncovered how a testis-specific protein contributes to tumor growth and progression when it is mis-expressed in lung cancer, according to a study published in Science Advances.
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Study Identifies Link Between Body Clock Disruption and Metabolic Disease
Northwestern Medicine investigators have discovered how disruptions in circadian rhythm in our muscles combined with poor diet can contribute to the development of diabetes, according to a recent study published in Proceedings of the National Academy of Sciences.
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New Function Discovered for Protein Important in Leukemia
A new study has identified a previously unobserved function of a protein found in the cell nuclei of all flora and fauna, playing a role promoting gene transcription.
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Study Identifies Potential Therapeutic Target for Colon Cancer
Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced tumor growth and improved survival, underscoring the potential of a new therapeutic target for colon cancer, according to a recent study published in Science Advances.
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Reprogramming Compromised Immune Cells to Fight Cancer
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to work against tumors, according to a study published in Science Advances.
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Genomic ‘Memory’ Governs the Building Blocks of Life, Study Reveals
Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating the building blocks of life, according to a new study published in Science Advances.
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Uncovering the Molecular Drivers of B-cell Lymphoma Tumor Growth
Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a study published in the Journal of Clinical Investigation.
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Novel Mechanism Eliminates ‘Bad’ Enzyme During Gene Expression
Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates ‘bad’ transcriptional elongation enzymes during gene expression, findings that may inform the understanding of adrenal diseases, according to a recent study published in Science Advances.
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Transcription Factor Binding Sites May Help Explain Underlying Causes of Many Diseases
Investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, findings that may improve the understanding of underlying causes of developmental disorders and cancer, according to a recent study.
