A machine-learning program called Peakachu can reveal previously unknown chromatin loops, according to a Northwestern Medicine study published in Nature Communications.
Northwestern Medicine investigators have discovered that the growth of cancerous tumors requires the activation of a specific biochemical process within the mitochondria of tumor cells, showing potential as a new target for cancer therapy.
In the past decade, synthetic biology — the reengineering of organisms and their genetic information so they can produce a new substance or gain a new ability — has rapidly emerged to the forefront of modern-day science. Northwestern’s Center for Synthetic Biology has been leading the way.
A new $15 million gift from University trustees and supporters Louis A. Simpson and Kimberly K. Querrey will establish the Simpson Querrey Institute for Epigenetics at Northwestern University Feinberg School of Medicine, boosting the school’s current efforts to study the effects of environment on the regulation of gene expression.
A DNA transcription mechanism does not work as previously thought, according to a new Northwestern Medicine study.
Using mathematical modeling and optical imaging they developed themselves, a Northwestern University research team has discovered how chromatin folds at the single-cell level.
A new Northwestern University study has discovered that the packing of the three-dimensional genome structure, called chromatin, controls how cells respond to stress.
A study published in the Journal of Cell Biology showed that mitochondrial stress in neurons can cause an enzyme imbalance that contributes to neuronal dysfunction and death.