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First Potential Immunization Against RSV for Healthy Infants Found Highly Effective in Phase 3 Trial
A new drug has been shown to be highly effective against pediatrics infections caused by respiratory syncytial virus (RSV).
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Racial and Neighborhood Disparities in Breast Cancer
Black women with early hormone receptor-positive breast cancer experienced shorter relapse-free intervals and overall survival compared with white women, according to findings published in JAMA Oncology.
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Second-year Medical Students Help Address Food Insecurity
As part of their second-year MD curriculum, a group of Feinberg students recently designed and implemented a community quality improvement project on food insecurity.
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Glucocorticoids Enhance Muscles Through Sex-Specific Pathways
Glucocorticoid steroids improved muscle performance through distinct, sex-specific mechanisms, according to a Northwestern Medicine study.
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Potassium Channel Dysfunction in Genetic Epilepsy
Northwestern Medicine scientists discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy.
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Proactive Machine Learning Could Speed Healthcare Innovation
Shifting machine learning workflows to a proactive model could speed data collection and analysis, according to a viewpoint published in JAMA.
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Good Outcomes in COVID-19 Lung Transplants
Patients with COVID-19-associated lung disease who received lung transplants had similar outcomes compared to patients without COVID-19, according to a study published in JAMA.
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Intensive Crohn’s Treatment is Safe
Intensive treatment for patients with Crohn’s disease showed no safety differences compared to the current standard of care.
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Investigators Identify New Connections Between Circadian Rhythm and Muscle Repair
Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury.
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Optimizing Balance of Treatments in Prostate Cancer
Patients receiving radiotherapy to treat high-risk prostate cancer benefit from androgen deprivation therapy, and length of treatment may be dependent on radiation deliver, according to a recent study.
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Genetics of Eosinophilic Colitis Revealed
A genetic analysis indicates eosinophilic colitis is distinct from other eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a recent study.
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New Treatment for Metastatic Hormone-Sensitive Prostate Cancer
The drug darolutamid, administered with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer.
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Investigating Prevalence Risk of Familial Heart Failure
Idiopathic dilated cardiomyopathy (DCM) was found to have a familial etiology in 30 percent of individuals diagnosed with DCM, and the overall risk for a family member of developing DCM was nearly 20 percent by the age of 80.
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Possible Third Cure To HIV: Progress in a Time of Regression
Associate vice president of research Richard D’Aquila, MD, shares his perspective on the news of a possible third person cured of HIV, and the progress of HIV research in the future.
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SARS-CoV-2 Infection Increases Risk of Maternal Mortality and Obstetric Complications
Pregnant and postpartum individuals infected with SARS-CoV-2 during pregnancy have an increased risk of maternal mortality or morbidity from obstetric complications, according to a recent study.
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Drug Combination Fails to Improve Outcomes in Influenza
A new combination of antiviral drugs did not improve clinical outcomes in hospitalized patients with severe influenza, warranting further investigation into new therapeutic strategies, according to a recent clinical trial.
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Elucidating Parkinson’s Disease
Recent advances from Northwestern investigators have powered a new, deeper understanding of Parkinson’s disease that could pave the way to a disease-modifying treatment.
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Locoregional Therapy Does Not Improve Breast Cancer Survival
Treating breast tumors alongside distant metastases did not improve outcomes in women with stage IV breast cancer, according to a new study.
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Northwestern Study Honored by Clinical Research Forum
Robert Kushner, MD, ’80, ’82 GME, was honored for a study published in NEJM with a 2022 Top 10 Clinical Research Achievement Award.
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Novel Combination Therapy May Extend Pancreatic Cancer Survival
A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients.