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Study Evaluates Treatment Interventions for Severe Obesity in Adolescents
Adolescents with severe obesity who received meal replacement therapy plus financial incentives experienced a greater reduction in body mass index compared to those who received meal replacement therapy alone, according to recent findings published in JAMA Pediatrics.
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Understanding Molecular Drivers of Lymphedema
Northwestern Medicine scientists have uncovered molecular mechanisms underlying lymphatic valve development, a discovery which could prove useful in treating lymphedema, according to a study published in The Journal of Clinical Investigation.
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Exploring CAR T-cell Therapy for Aggressive Follicular Lymphoma
CAR T-cell therapy is an effective treatment for aggressive subtypes of follicular lymphoma, according to a clinical trial published in Nature Medicine.
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Incoming PA Program Students Participate in White Coat Ceremony
The Feinberg Physician Assistant Program’s Class of 2026 recently celebrated the beginning of their medical journey with a white coat ceremony.
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Northwestern Hospitals Once Again Rank Among Best in the Nation
In its latest annual Best Hospitals rankings, U.S. News & World Report has once again recognized Northwestern Medicine hospitals as some of the best in the nation.
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Subcutaneous Therapy Improves Inflammatory Bowel Disease Treatment
Subcutaneous delivery of an anti-TNF inhibitor therapy improved remission rates compared to placebo in patients with moderate-to-severe Crohn’s disease and ulcerative colitis who previously completed intravenous anti-TNF therapy, according to clinical trial results published in the journal Gastroenterology.
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The Heart Health Benefits of Urban Green and Blue Spaces
New Northwestern research shows that being near and having more exposure to urban green space and blue (water) space is linked to lower odds of having coronary artery calcification in middle age.
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Understanding the Role of RNA Methylation in Cancer
RNA modifications could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell which sheds new light on the complex process underlying RNA transcription.
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Scientists Discover a Cause of Lupus and a Possible Way to Reverse It
Scientists have discovered a molecular defect that promotes the pathologic immune response in lupus and demonstrated that reversing the defect may potentially reverse the disease.
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Intracellular Mechanisms Promote Spread of Deadly Bacterial Infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in Proceedings of the National Academy of Sciences.
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Remembering Pioneering Pharmacologist V. Craig Jordan
V. Craig Jordan, PhD, the groundbreaking pharmacologist known as the “father” of breast cancer drug Tamoxifen, has died at 76.
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Blood Test Could Provide Snapshot of Overall Health
Circulating protein levels may serve as a biomarker for cardiorespiratory fitness, an important but previously hard-to-measure component of overall health, according to a study published in Nature Medicine.
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B Vitamins May Help Those with Artery Disease Walk Farther
Vitamin B3 supplements may help people with peripheral artery disease walk farther, according to a Northwestern Medicine-led clinical trial published in Nature Communications.
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Medical Student Investigates Racial and Ethnic Disparities in Medicaid Disenrollment
Kranti Rumalla, a second-year medical student at Feinberg, was the lead author of a study that found racial disparities among patients who were disenrolled from Medicaid coverage after the end of the COVID-19 Public Health Emergency.
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Protein May Hold Key to Transplant Tolerance
Northwestern Medicine investigators have uncovered how a single protein contributes to heart transplant tolerance in mice, according to a study published in the Proceedings of the National Academy of Sciences.
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Combination Therapy May Improve Outcomes for Advanced Bladder Cancer
Patients with immunotherapy-resistant bladder cancer who received a novel combination treatment demonstrated improved response to treatment, according to a recent study published in Nature Medicine.
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New Cellular Mechanisms in Parkinson’s Disease Discovered
A pair of recent studies led by Joseph Mazzulli, PhD, have uncovered previously unknown cellular mechanisms involved in neuronal protein aggregation and misfolding, key characteristics of Parkinson’s disease, which may serve as therapeutic targets.
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Embryo’s Signaling Mechanism May Promote Healthy Aging, Combat Neurodegenerative Diseases
Northwestern investigators have identified a novel transcription factor which regulates a signaling mechanism utilized by a fertilized embryo to protect its mother from cellular and environmental stress, according to a recent study to published in the journal Genes and Development.
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Center for Engineering in Vision and Ophthalmology Marks Launch with Symposium
Northwestern’s Center for Engineering in Vision and Ophthalmology recently celebrated its launch with a symposium focused on the work of next-generation engineers and physicians.
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Improving Measurement of Gene Expression in Single Cells
Northwestern Medicine scientists have developed a new technique to identify individual cells for RNA sequencing, which will empower scientists to gather more accurate and precise scientific data, according to details published in Cell Genomics.