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One in Three Middle-Aged Adults Struggle With Basic, ‘Everyday’ Health Tasks
One in three middle-aged American adults ages 35 to 64 cannot consistently read prescription instructions correctly, understand medical forms or recall details from doctor visits involving chronic condition diagnoses, according to a recent study.
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Lymphatic Dysfunction Drives Heart Valve Disease
Dysfunction in the lymphatic system has been identified as a hidden driver of life‑threatening heart valve disease in patients with Marfan syndrome, according to a new Northwestern Medicine study published in The Journal of Clinical Investigation.
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Immune Cell Circuit Restores Barrier Function in IBD
Scientists have discovered a new communication circuit between immune cells in the intestines, a potential therapeutic target to improve inflammatory bowel disease outcomes, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Expanding the Evidence for Behavioral Interventions in Gastroenterology
The Division of Gastroenterology and Hepatology at Feinberg has a distinct strength in understanding how behavior and lifestyle influence gastrointestinal (GI) health. The Division conducts research aimed at improving treatments for disorders of the digestive tract and related organs.
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Exploring Intracellular Communication to Understand Neurodegeneration
Investigators have uncovered a new communication pathway between mitochondria and RNA granules that may improve the understanding of how the toxic buildup of the TDP-43 protein leads to the development of certain neurodegenerative diseases, according to a recent study published in Nature Communications.
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Bacteria ‘Rewire’ Epithelial Cells and Drive Disease in the Gut
A bacterial pathogen that causes colitis and colorectal cancer creates a nutrient-rich niche and “rewires” epithelial cell signaling in the inflamed gut, which promotes bacterial colonization and disease, mechanisms that may be promising therapeutic targets, according to a recent study published in the journal Cell.
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Mateen Appointed Director of New Center for Global Neurology
Farrah Mateen, MD, PhD, chief of the Division of Multiple Sclerosis & Neuroimmunology and the Dr. Charles L. Mix Research Professor of Neurology, has been named director of the Center for Global Neurology, a center of the Robert J. Havey, MD Institute for Global Health (IGH).
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Physiological Factors Reshape How Drugs and Proteins Interact
A new Northwestern Medicine study has demonstrated that proteins studied in simplified laboratory conditions don’t behave the same way in the human body, according to the study published in Nature Structural and Molecular Biology.
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Immune Biomarkers May Predict Response to Bladder Cancer Treatment
A Northwestern Medicine study has offered new clues as to why immunotherapy works well for some bladder cancer patients but fails for others, according to a study published in the Journal of Clinical Investigation.
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Hormone Impacts Red Blood Cell Production in Anemia
Northwestern Medicine scientists have discovered that the hormone FGF23 reduces the production of red blood cells and may contribute to the development of anemia of chronic kidney disease, according to a recent study published in Blood.
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Blood Test May Predict Immunotherapy Response in Head and Neck Cancer
A new Northwestern Medicine study suggests that a simple blood test could help identify which patients with head and neck cancer are most likely to benefit from immunotherapy, according to a study published in the Journal of Clinical Investigation.
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Overlooked DNA Structures Help Organize the Genome
Northwestern Medicine scientists have discovered that little-studied DNA structures play a central role in organizing the human genome and controlling gene activity, according to a new study published in the Proceedings of the National Academy of Sciences.
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Novel Synthetic Biomolecule Degrades Disease-Related Proteins
Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can target and degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study.
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NUCATS and NICO Symposium Sparks Interdisciplinary Collaboration
Recently, the Symposium to Empower High-Priority Research Collaborations, organized by the Northwestern University Clinical and Translational Sciences Institute and the Northwestern Institute on Complex Systems, focused on addressing critical challenges in human health and disease through team-based approaches.
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Study Uncovers Potential Gene Therapy for Late-Stage Parkinson’s Side-Effects
Northwestern Medicine scientists have discovered that suppressing excitatory synaptic transmission in a small group of neurons in the brain may reverse levodopa-induced dyskinesia in patients with late-stage Parkinson’s disease without reducing the symptomatic benefits of levodopa treatment, according to a recent study published in Neuron.
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Alzheimer Day Highlights Research Advances and Community Engagement
Faculty, clinicians, investigators and community members gathered on May 19 for Alzheimer Day, an annual conference dedicated to advancing understanding of dementia and connecting cutting-edge research with patients and families.
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Asthma Drug Improves Treatment of Aggressive Cancers in Preclinical Studies
A drug widely used to treat asthma and allergies may also help fight aggressive cancers, reports a new Northwestern Medicine study that uncovered how tumors hijack common white blood cells to evade immunotherapy.
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Wearable Polygraph Detects Hidden Stress
Northwestern University engineers have developed a small, wireless polygraph system you can wear, designed to sense underlying stress hidden deep within the body.
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‘Toxic’ Molecule Plays Vital Role in Gene Regulation and Development
A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions.
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Policing Plagiarism of Ideas in Generative AI-Assisted Research Writing
A new publication argues that AI-assisted plagiarism in manuscript writing harms the research environment by eroding trust among scientists, misrepresenting the origin and authenticity of scholarly work, and discouraging innovation and original inquiry.