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Decorated Nanoparticles Prevent Allergic Reactions
Northwestern University scientists have developed the first selective nanoparticle therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.
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Experimental Drug May Slow Childhood Brain Tumors
The drug tovorafenib may halt the growth of or shrink some childhood brain tumors, according to a clinical trial published in Nature Medicine.
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New Cause of Neuron Death in Alzheimer’s Discovered
A new Northwestern Medicine study has identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains.
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‘Father of Microbiome Research’ Awarded 2024 Nemmers Prize in Medical Science
Jeffrey Gordon, MD, a distinguished university professor at Washington University in St. Louis, who is often referred to as the “father of microbiome research,” is the recipient of the 2024 Mechthild Esser Nemmers Prize in Medical Science at Northwestern University.
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New 3D Spatial Approach Reveals Interactive View of Glioblastoma and Therapeutic Targets
A multidisciplinary team of investigators has developed a first-of-its-kind interactive 3D spatial approach that reveals new therapeutic targets and provides a comprehensive three-dimensional view of glioblastoma tumors, detailed in a recent study published in Cell.
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Northwestern Medical Orchestra Sees Strong Growth, Unites Feinberg and Bienen
The Northwestern Medical Orchestra entered its seventh year with growth in participants and audience alike, and a performance of a composition by Bienen School of Music’s new dean, Jonathan Bailey Holland.
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Nearly 40% of Type 2 Diabetes Patients Stop Taking Their Second-Line Medication
Nearly two-thirds of patients with diabetes either discontinued their second-line medication, switched to a different medication class or intensified their treatment, according to a recent study.
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Novel Protein Interactions May Serve as Biomarker for Heart Disease
Investigators led by Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart’s atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.
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Novel Regulator of Immune Evasion in Cancer Identified
Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Neural Mechanisms May Serve as Therapeutic Target for Depression
A recent study published in Molecular Psychiatry has identified previously unknown alterations in neural connectivity that promote psychomotor disturbance — a slowing or reduction in movement — in individuals with major depressive disorder.
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Mustanski Appointed as Advisor to NIH Director
Brian Mustanski, PhD, director of the Institute for Sexual and Gender Minority Health and Wellbeing, has been appointed to the Advisory Committee to the Director of National Institutes of Health.
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Subset of Neurons Allow Eyes to Detect Motion
Northwestern Medicine scientists have identified how a subset of neurons enable the eyes to perceive motion, according to a study published in Nature Communications, a discovery that reveals previously hidden complexities of how vision functions in mammals.
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Building Momentum Toward Neural Prostheses
Several recent studies from Feinberg investigators and colleagues have shed light on complex neurological processes and provided new insights and technological developments for neural prostheses.
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Kwasny Recognized by the American Statistical Association
Mary Kwasny, ScD, professor of Preventive Medicine in the Division of Biostatistics, has received the American Statistical Association’s (ASA) Founders Award, the highest award the organization bestows for distinguished service.
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Exploring How Antibiotic-Resistant Bacteria Become Aggressive
Some strains of an antibiotic-resistant bacteria may not turn out to be as aggressive as previously thought, according to a Northwestern Medicine study recently published in Nature Communications.
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Defining Rheumatoid Arthritis Subtypes May Improve Treatments
By profiling the inflammatory cells types in joint tissue biopsy samples, scientists have characterized six subtypes of rheumatoid arthritis, an approach that could help physicians tailor more effective treatment strategies for patients based on disease type, according to findings published in Nature.
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New Brain-Like Transistor Mimics Human Intelligence
Taking inspiration from the human brain, scientists have developed a new synaptic transistor capable of higher-level thinking, according to results published in the journal Nature.
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Novel ‘Feeding’ Mechanism Promotes Glioblastoma Treatment Resistance
Northwestern Medicine investigators have discovered that specialized immune cells within the glioblastoma tumor microenvironment use a unique “feeding” mechanism that promotes tumor growth and treatment resistance, according to findings published in the journal Cell Metabolism.
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2023 Year in Review
Feinberg experienced a year of outstanding growth, scientific achievement, and collaboration in 2023, from honors and awards to unprecedented research discoveries.
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Localized Genetic Mutations May Serve as Biomarker for Wide Range of Cancers
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
