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Study Discovers Novel Biomarker for Vascular Aging and Neurodegeneration
Decreased activity of a specific signaling pathway in the brain vessels of aging mice and humans was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.
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Semaglutide Trials Show Improvements in Cardiovascular Health, Quality of Life
Two years after the FDA’s approval of semaglutide for chronic weight management, Northwestern Medicine scientists remain at the forefront of investigating the drug’s potential in helping patients who are overweight or have obesity who also have other preexisting health conditions.
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Exploring How Poxviruses Dismantle Antiviral Responses
Northwestern Medicine investigators led by Derek Walsh, PhD, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, according to findings published in Nature Communications.
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Feinberg Names New Associate Dean for Student Affairs
Eli Zimmerman, MD, has been named associate dean for student affairs at Feinberg, effective January 1, 2024.
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Top 3 Breakthroughs Podcasts of 2023
The Breakthroughs podcast released 19 episodes in 2023 on topics ranging from implementation science and ChatGPT to new insights in dopamine and AI in healthcare. The top three most downloaded episodes this year were on varying topics including exercise and Parkinson’s disease, food allergies and recent discoveries about mitochondria.
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Developing Deep Learning Models to Understand the Human Genome
Northwestern Medicine scientists have developed a deep learning algorithm accelerating research around diseases and disorders that occur when the process of DNA transcription goes awry.
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Medical Student Variety Show Supports Chicago Street Medicine
Medical students shared laughs and poked fun at the medical school experience during the annual performance of In Vivo, Feinberg’s sketch comedy and variety show, held on December 8.
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Krainc, Kelley Elected to National Academy of Inventors
Dimitri Krainc, MD, PhD, the Aaron Montgomery Ward Professor and chair of the Davee Department of Neurology and director of the Simpson Querrey Center for Neurogenetics, has been elected to the National Academy of Inventors.
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Bone Transcription Factor Controls Nervous System Gene Expression
An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.
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Evolving Telehealth Research and its Place in Healthcare Delivery
Since the COVID-19 pandemic thrust many providers into telehealth appointments, scientists have been asking questions about the benefits and concerns of telehealth. While telehealth was in use and gathering interest prior to the pandemic, the need for it accelerated during a time when people were encouraged to stay home.
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Global Health Day Highlights Pandemic, HIV Research
Northwestern investigators, faculty, students and community partners came together to share and celebrate global health research, education and outreach as part of the Robert J. Havey, MD Institute for Global Health’s 12th annual Global Health Day.
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AI May Spare Breast Cancer Patients Unnecessary Treatments
A new AI tool may make it possible to spare breast cancer patients unnecessary chemotherapy treatments by using a more precise method of predicting their outcomes, reports a new Northwestern Medicine study published in Nature Medicine.
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Drug Extends Survival in Prostate Cancer with Genetic Mutations
Men with hormone-resistant prostate cancer and specific genetic mutations who were treated with the drug olaparib survived longer than men treated with traditional hormone therapy, according to a post hoc analysis published in the Journal of Clinical Oncology.
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Pioneering Biochemist Craig Crews Named Winner of 2024 Kimberly Prize
Northwestern University Feinberg School of Medicine and the Simpson Querrey Institute for Epigenetics announced today that renowned biochemist Craig M. Crews, PhD, who pioneered the pharmaceutical field of targeted protein degradation, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
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Family Language Tied to Hospitalization Rates in Feverish Babies
Babies of parents who speak a language other than English may be more likely to be unnecessarily hospitalized when visiting the emergency department for high fevers, according to a recent study published in JAMA Pediatrics.
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New Therapeutic Strategies for Spinal Muscular Atrophy
Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences (PNAS).
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Investigating Drug Combinations for Heart Failure
A common diabetes medication may help some patients with treatment-resistant hypertension slightly lower their high blood pressure and lessen their risk of heart failure events such as stroke, according to an analysis of a clinical trial published in Circulation.
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Comparing Cardiac Monitoring Methods to Detect Atrial Fibrillation After Stroke
Insertable cardiac monitors detected a higher incidence of atrial fibrillation in patients with prior ischemic stroke over a three-year period than standard medical monitoring methods, according to results published in JAMA Neurology, based on long-term findings from the Northwestern Medicine-led STROKE AF clinical trial.
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Using Gene Expression to Predict if a Brain Tumor is Likely to Grow Back
Scientists have found a highly accurate way to predict the best cancer treatment for patients based on patterns of gene expression in their tumors.
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Immigrants Living in the U.S. Have Fewer Preterm Births
Individuals born in the U.S. had a higher rate of giving birth prematurely compared to U.S. immigrants, a new Northwestern Medicine study has found.
