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Novel Molecular Mechanisms Inform Targeted Therapies for Chronic Kidney Disease
A recent Northwestern Medicine study has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common type of polycystic kidney disease, according to findings published in Proceedings of the National Academy of Sciences.
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First Study to Use Consumer Wearables to Predict Pediatric Surgery Complications
A new study published in Science Advances is the first to use consumer wearables to quickly and precisely predict postoperative complications in children and shows potential for facilitating faster treatment and care.
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Northwestern Accepting Nominations for $350,000 Nemmers Prize in Medical Science
Northwestern University is accepting nominations for its $350,000 Mechthild Esser Nemmers Prize in Medical Science. The biennial prize will be awarded in fall 2026.
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Tracking Proteins That Help the COVID-19 Virus Replicate
Scientists have identified dozens of human proteins that SARS-CoV-2, the virus that causes COVID-19, depends on to replicate and spread, according to a recent study published in the journal PLOS Biology.
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Gestational Diabetes May Signal Poor Prepregnancy Cardiovascular Health
Poor prepregnancy cardiovascular health is associated with a higher risk of developing gestational diabetes and coronary artery calcium in midlife, according to a recent Northwestern Medicine study.
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Investigating Nationwide IV Shortages After Hurricane Helene
Intravenous fluid use in pediatric emergency departments decreased nationwide following Hurricane Helene, according to a recent Northwestern Medicine study, findings that may help emergency departments better allocate resources.
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AI Matches Doctors in Mapping Lung Tumors for Radiation Therapy
Northwestern Medicine scientists have developed an AI tool that not only matches doctors in accurately outlining lung tumors on CT scans but can also identify areas that some doctors may miss, according to a new study.
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How a Common Metabolite Worsens Inflammatory Bowel Disease
Northwestern Medicine investigators have identified a surprising culprit in the progression of inflammatory bowel disease, according to a study published in Nature Immunology.
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Diabetes Drug May Serve as Alternative Treatment Option for Hydrocephalus
A drug commonly used to treat diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, according to a study published in the Journal of Clinical Investigation.
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AI Imaging Approach May Help Identify Parkinson’s Sooner
An artificial intelligence-based imaging approach may be an effective tool for distinguishing patients with Parkinson’s disease from those with other closely related diseases sooner than current methods, according to a recent study published in JAMA Neurology.
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Novel Mechanism Reduces Epithelial Cell Damage and Loss
Northwestern Medicine scientists have discovered a previously unknown process used by epithelial cells to alleviate epithelial tissue crowding and avoid cell damage and loss, according to a recent study published in Nature Communications.
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New Targets for Treating Blood Disorders
Northwestern Medicine scientists have uncovered key details about a group of rare but serious blood disorders, according to a study published in the Journal of Clinical Investigation.
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Wearable Sleep Monitoring Device May Improve Detection of Sleep Disorders
Northwestern scientists have developed a wearable wireless device to monitor sleep, which may improve the detection of sleep disorders, detailed in recent study in the Proceedings of the National Academy of Sciences.
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Antimicrobial Resistance Expert to Lead Division of Infectious Diseases
Jennie H. Kwon, DO, MSCI, associate professor of medicine at Washington University in St. Louis, has been named the Gene Stollerman Professor and Chief of the Division of Infectious Diseases, effective October 2025.
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How Hair Follicles Sense Their Environment
Northwestern Medicine scientists have discovered how cells responsible for hair growth perceive physical forces in their environment and utilize this information to regulate their behavior, according to a study published in Science Advances.
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New ‘Molecular GPS’ Will Fast-Track Drug Discovery
Scientists at Northwestern University have developed the largest open-access resource of its kind to help investigators shave off months of early-stage drug development time, detailed in research published in Science Advances.
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Insulin Pump Improves Glucose Levels in Patients with Type 2 Diabetes
The use of an automated insulin delivery system in patients with type 2 diabetes resulted in a greater reduction in glucose levels compared to usual care plus continuous glucose monitoring, according to a recent clinical trial published in the New England Journal of Medicine.
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Developing New Methods to Map Brain-Wide Synaptic Changes
Scientists have developed a new method to track changes in synaptic protein lifetimes across the entire brain, according to a study published in Nature Neuroscience.
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Taking the Science to Market: Start-ups at Feinberg
This story was originally published in the June 2025 issue of the Breakthroughs newsletter. Every year at Feinberg, a handful of start-up companies are born from discoveries in the lab. Paperwork is filed for hundreds of inventions and patents; patents are issued and the process for optioning and licensing technology through Northwestern’s Innovations and New Ventures[…]
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Study Uncovers Key Biological Markers in Severe Malaria
Scientists investigating severe malaria infections in children have uncovered key biological markers that could help guide future treatments, according to a study published in Nature Communications.