Cardiovascular disease is the leading cause of pregnancy-related deaths in the U.S. According to a new Northwestern Medicine study published in the journal Circulation, about sixty percent of pregnant women in the U.S. have poor heart health. Study authors Sadiya Khan, MD, and Natalie Cameron, MD, explain the results of the study and what needs to be done to reverse this alarming trend.
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In response to the first successful animal heart transplant into a human patient, internationally renowned transplant surgeon Satish Nadig, MD, PhD, reviews some of the scientific developments that have culminated in this moment and stresses the ongoing need for other experimental strategies. Nadig is also the new director of Feinberg’s Comprehensive Transplant Center.
Since coming to Northwestern in 2013, Deborah Smith Clements, MD, chair of the Department of Family & Community Medicine, has established three thriving family medicine residency programs and has been an advocate for improving the residency match process, health policy and social justice. She talks about her work, leading her department through COVID-19 and her recent Distinguished Service Award from Illinois Academy of Family Physicians.
Gregory Smith, PhD, professor of Microbiology-Immunology at Feinberg, has been investigating a path to long-needed vaccine development for herpes virus. He recently published findings in the journal Nature that bring the possibility of a preventive vaccine a step closer.
Immunotherapy has revolutionized cancer treatment over the last few decades, though not for glioblastoma — the most common and deadly malignant brain tumor. However, Northwestern Medicine neurosurgeon Adam Sonabend, MD, shares promising research on the potential benefits of immunotherapy for certain glioblastoma patients.
What do we know about the effectiveness of COVID-19 boosters, and how might they better protect us from new variants such as omicron? Alexis Demonbreun, PhD, assistant professor of Pharmacology, offers insight. She is the author of a new study that shows COVID-19 boosters seem to supercharge antibody response.
Millions of molecular proteins are swimming through our body’s cells and many studies have discovered that these proteins are the main drivers of all human diseases. Scientists are now mapping proteins the way the Human Genome Project mapped genes. Neil Kelleher, PhD, director of Northwestern Proteomics, is at the forefront of the Human Proteoform Project and explains how it could lead to more targeted and effective diagnostics and treatments for diseases.
Regenerative nanomedicine is being used to develop new therapies for devastating conditions such as severe spinal cord injuries. Northwestern’s Samuel Stupp, PhD, is a pioneer in the field of regenerative nanomedicine and recently published a paper in the journal Science that details how a new injectable therapy uses synthetic nanofibers to reverse severe spinal cord injuries in animals and how this therapy could soon be used in humans.
Northwestern Medicine scientists have discovered one of the earliest signs of Parkinson’s disease, proving that damaged neuronal mitochondria alone can cause symptoms of the disease, according to a study published in Nature. Senior author D. James Surmeier, PhD, chair of the Feinberg department of Neuroscience, who has over 30 years of experience in the field, explains the importance of these findings for future Parkinson’s research and therapeutics.
People who are Black make up the largest group of minorities in need of an organ transplant. In 2019, Northwestern Medicine launched the African American Transplant Access Program to help address this problem. Founding director of the program Dinee Simpson, MD, talks about the barriers to organ transplant for Black patients and how she is working to bring down those barriers in Chicago.