
What do we know about the effectiveness of COVID-19 boosters, and how might they better protect us from new variants such as omicron? Alexis Demonbreun, PhD, assistant professor of Pharmacology, offers insight. She is the author of a new study that shows COVID-19 boosters seem to supercharge antibody response.

Millions of molecular proteins are swimming through our body’s cells and many studies have discovered that these proteins are the main drivers of all human diseases. Scientists are now mapping proteins the way the Human Genome Project mapped genes. Neil Kelleher, PhD, director of Northwestern Proteomics, is at the forefront of the Human Proteoform Project…

Immunotherapy has revolutionized cancer treatment over the last few decades, though not for glioblastoma — the most common and deadly malignant brain tumor. However, Northwestern Medicine neurosurgeon Adam Sonabend, MD, shares promising research on the potential benefits of immunotherapy for certain glioblastoma patients.

Northwestern Medicine scientists have discovered one of the earliest signs of Parkinson’s disease, proving that damaged neuronal mitochondria alone can cause symptoms of the disease, according to a study published in Nature. Senior author D. James Surmeier, PhD, chair of the Feinberg department of Neuroscience, who has over 30 years of experience in the field,…

Judd Hultquist, PhD, talks about key variants of SARS-CoV-2 and how his lab is identifying and studying these variants.

As heart conditions like arrhythmia become increasingly common, heart monitoring is becoming an even more important tool for disease prevention and treatment. Northwestern Medicine cardiac electrophysiologist Rod Passman, MD, who has over three decades of experience in the field, reviews the history of cardiac monitoring and looks to the future. He details his pioneering use…

As the Delta variant of SARS-CoV-2 is causing breakthrough infections in some vaccinated people around the world, scientists at Northwestern Medicine are developing and studying potential next-generation COVID-19 vaccines that could be more effective at preventing and clearing breakthrough infections. Pablo Penaloza-MacMaster, PhD, an assistant professor of Microbiology-Immunology at Feinberg, discusses work in his lab…

People who are Black make up the largest group of minorities in need of an organ transplant. In 2019, Northwestern Medicine launched the African American Transplant Access Program to help address this problem. Founding director of the program Dinee Simpson, MD, talks about the barriers to organ transplant for Black patients and how she is…

Elizabeth McNally, MD, PhD, talks about her recent discoveries advancing muscular dystrophy research.

An early clinical trial found that a spherical nucleic acid drug developed at Northwestern kills tumor cells in people with the fatal brain cancer glioblastoma. This is the first time a nanotherapeutic has been shown to cross the blood-brain barrier and cause cell death. Lead investigator Priya Kumthekar, MD, explains the results of the study.