Category: Scientific Advances
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Genetic Mechanisms May Reveal Retinal Vascular Disease Therapeutic Targets
Northwestern Medicine investigators have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve as therapeutic targets for retinal vascular disease, according to findings published in Nature Communications.
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Improving Models to Study the Human Heart
Northwestern Medicine scientists have developed a new method of measuring and optimizing the maturation process of cultured heart cells, an approach that will set the future standard for a commonly used cell model in scientific research, according to details published in Cell Reports.
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Leading Prostate Cancer Research for More than 20 Years
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center…
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How Herpes Hijacks a Ride into Cells
Northwestern Medicine scientists have discovered how herpes viruses hijack cellular transport processes to infiltrate the nervous system, according to a study published in the Proceedings of the National Academy of Sciences.
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Understanding Cellular Transcription Responses to Oxygen Deprivation
A multiprotein complex is essential for regulating cellular transcription response to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.
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Developing Tools to Explore DNA Methylation
A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.
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Probing Deeper to Understand Protein Expression in Neurons
Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron type, according to a study published in Molecular Psychiatry.
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Novel Biological Mechanism Discovered That Could Lead to New Treatments for Neurological Disorders, Cancers
The lab of Yongchao C. Ma, PhD, has discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers.
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Tracking the Evolution of COVID-19
Scientists have developed a machine-learning approach to track the evolution of the COVID-19 virus and potentially others, according to a study published in the Proceedings of the National Academy of Sciences.
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Novel Role for Metabolites in Cellular Metabolism Discovered
Investigators led by Issam Ben-Sahra, PhD, have discovered how cellular metabolism fluctuates in response to changes in levels of pyrimidines, metabolites used by cells to make DNA and RNA, according to a recent study published in Science.
