Category: Scientific Advances
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Engineering Human Heart Tissue for Scientific Study
Northwestern Medicine scientists have developed a new way to measure heart contraction and electrical activity in engineered human heart tissues, according to findings published in Science Advances.
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Understanding the Molecular Players in Eye Inflammation
Northwestern Medicine investigators have shed new light on how white blood cells in the retina function during inflammation and possibly during retinal vascular diseases with inflammatory components like diabetic retinopathy, according to a study recently published in the Journal of Clinical Investigation.
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New Biomaterial Regrows Damaged Cartilage in Joints
A new bioactive material developed by Northwestern scientists may be able to regenerate high-quality cartilage in knee joints, according to a new study.
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Investigating the Molecular Mechanisms of ‘Forgetting’
Northwestern Medicine investigators have uncovered a new way in which neurons in the brain “forget” associations that help guide behavior and habits, according to a study published in Cell Reports.
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Intercellular Mechanisms Regulate Gene Expression in Cancer Cells
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
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Understanding Epigenetic Control of Antibody Responses
Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.
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‘Feedback Loop’ Promotes Cancer Cells’ Adaption to Molecular Stress
Investigators from the laboratory of Marc Mendillo, PhD, have discovered new cellular regulators of an established cancer cell transcription factor linked to cancer cell resilience and tumor progression, according to findings published in the Proceedings of the National Academy of Sciences.
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Novel AI Model May Enhance Health Data Interoperability
An AI model developed by Northwestern Medicine investigators improved the transformation of EHR data into standardized health resources more efficiently than current methods, according to a recent study published in journal NEJM AI.
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Developing New Methods for Targeted Protein Degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology.
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Mitochondria Support Immune Response to Central Nervous System Injuries
Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of immune cells called microglia, but do help them respond to demyelinating injury, according to a study published in Nature Metabolism.
