Category: Scientific Advances
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Transcription Factor Binding Sites May Help Explain Underlying Causes of Many Diseases
Investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, findings that may improve the understanding of underlying causes of developmental disorders and cancer, according to a recent study.
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Mitochondria May Be a Promising Therapeutic Target for Inflammatory Diseases
Northwestern scientists have discovered how mitochondria influence the body’s immune response through modulating specific cell signaling pathways, according to a recent study published in Science Advances.
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Novel Technique May Accelerate Study of Gene Regulation
Investigators from the laboratory of Ali Shilatifard, PhD, have developed a novel technique to precisely and efficiently study gene regulation, which may accelerate the development of new therapeutic strategies, according to a recent study published in Molecular Cell.
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Unravelling the Mysteries of Calcium Channel Regulation
Scientists have uncovered new insights into the molecular players behind calcium channel regulation, a biological process that coordinates a wide array of physiological responses, according to a study published in the Proceedings of the National Academy of Sciences.
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2024 in Scientific Imagery
From probing the human brain to elucidating mechanisms behind cellular responses, Feinberg investigators have provided stunning new snapshots of biological processes invisible to the naked eye.
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How Your Breathing Coordinates Brain Rhythms During Sleep
For the first time in humans, breathing rhythms during sleep have been linked to hippocampal brain waves that strengthen memory consolidation, according to a recent Northwestern study.
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Unlocking New Possibilities for Cancer Immunotherapy
Northwestern Medicine scientists have developed a method for identifying reactive cysteines on peptide antigens within the immune system, a development which may prove useful in cancer immunotherapy, according to a study published in Nature Communications.
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Shaking Sensor Continuously Monitors Inflammation
Northwestern University scientists have designed a new implantable device that can monitor fluctuating levels of proteins within the body in real time.
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Addressing the Growing Need for Implementation Science
Translating medical research findings from the research laboratory into patient care, otherwise known as from “bench to bedside,” is far more complex than it sounds, but is imperative to improve human health.
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Targeting Novel Molecular Mechanisms May Repair Damaged DNA
Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in cancer cells, findings that may inform the development of new targeted therapies for patients that have become resistant to standard treatments.
