Category: Scientific Advances
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Study Identifies New Molecular Mechanisms Supporting Cell Adhesion
Scientists led by Sergey Troyanovsky, PhD, professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process disrupted in a variety of skin and inflammatory diseases, according to a recent study published in the Journal of Cell Biology.
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Light Impacts How the Brain Perceives and Remembers Threats
Northwestern Medicine scientists have discovered that light plays a key role in how animals perceive environmental threats, findings that could improve the understanding of risk avoidance behaviors and disorders in humans, according to a recent study published in Nature Communications.
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Calcium Signaling Channels Regulate Neuroinflammation and Motivation
Northwestern Medicine scientists have discovered how calcium signaling channels in the brain’s immune cells regulate neuroinflammation and promote the development of behaviors associated with affective mood disorders, according to a recent study published in Science Signaling.
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Trashing Cancer’s ‘Undruggable’ Proteins
Northwestern scientists have developed polymers capable of grabbing proteins and directing them to the cell’s waste-disposal machinery, potentially triggering cancer cell death.
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Targeting Cellular Mechanisms May Improve Immune Response in Chronic Infections
Northwestern Medicine scientists have identified cellular mechanisms that cause immune cells to differentiate and ultimately lose function during viral infection, findings that could improve therapeutic strategies for controlling chronic infection, according to a recent study.
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AI Model May Improve RNA Sequencing Research
Scientists in the laboratory of Rendong Yang, PhD, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more accurately than conventional approaches, as detailed in a recent study published in Nature Communications.
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Cells’ Systems Cooperate to Form ‘Scaffolding’ During Egg Development
A Northwestern Medicine study has shed light on one of the most intricate construction projects in biology: how cells build and coordinate the internal scaffolding needed to create a healthy egg, according to a recent study published in the Journal of Cell Biology.
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New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve Targeted Therapies
Northwestern Medicine scientists have discovered new mechanisms underlying transcriptional initiation and elongation control that support proper gene expression, which may inform targeted therapeutic approaches for many diseases, according to a recent study published in Molecular Cell.
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Novel Mechanism Regulates Essential Enzyme Production in Kidneys
Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.
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Understanding the Link Between Nucleotide Metabolism and Chromatin Assembly
A Northwestern Medicine study has revealed a connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, according to findings published in Molecular Cell.
