Category: Scientific Advances
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Understanding Epigenetic Control of Antibody Responses
Northwestern Medicine investigators have uncovered how antibody responses are regulated by epigenetic factors commonly mutated in cancers, according to a study published in Nature Immunology.
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‘Feedback Loop’ Promotes Cancer Cells’ Adaption to Molecular Stress
Investigators from the laboratory of Marc Mendillo, PhD, have discovered new cellular regulators of an established cancer cell transcription factor linked to cancer cell resilience and tumor progression, according to findings published in the Proceedings of the National Academy of Sciences.
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Novel AI Model May Enhance Health Data Interoperability
An AI model developed by Northwestern Medicine investigators improved the transformation of EHR data into standardized health resources more efficiently than current methods, according to a recent study published in journal NEJM AI.
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Developing New Methods for Targeted Protein Degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology.
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Mitochondria Support Immune Response to Central Nervous System Injuries
Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of immune cells called microglia, but do help them respond to demyelinating injury, according to a study published in Nature Metabolism.
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Understanding the Role of RNA Methylation in Cancer
RNA modifications could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell which sheds new light on the complex process underlying RNA transcription.
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Protein May Hold Key to Transplant Tolerance
Northwestern Medicine investigators have uncovered how a single protein contributes to heart transplant tolerance in mice, according to a study published in the Proceedings of the National Academy of Sciences.
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Improving Measurement of Gene Expression in Single Cells
Northwestern Medicine scientists have developed a new technique to identify individual cells for RNA sequencing, which will empower scientists to gather more accurate and precise scientific data, according to details published in Cell Genomics.
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Investigating DNA Flexibility for the Creation of New Biomaterials
Northwestern investigators have demonstrated how manipulating DNA chemistry can alter its structure and flexibility and enable the realization of new materials useful in medicine and the life sciences, according to a study published in Science Advances.
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Transplant Research Thrives Through Collaboration
A map of the Northwestern University Transplant Outcomes Research Collaborative (NUTORC) Network looks like an intricate spiderweb. Hovering over one investigator’s name, you see the many investigators they are connected with through publications and research collaboration.
