Category: Scientific Advances
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Inhibiting a Metabolic Regulator in Specialized Immune Cells Increases Inflammation
Therapeutically inhibiting a metabolic regulator in monocytes unexpectedly increased inflammatory signaling, revealing mechanisms that could inform new strategies to treat chronic inflammatory disorders, according to a recent study.
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New Technique Improves Proteoform Imaging in Human Tissue
Investigators have developed a new imaging technique that increases the detection and identification of proteoforms by four-fold when compared to current methods.
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Feinberg Shares New Research Priorities
Four new research priorities have been identified, including synthetic biology, therapeutic development, social determinants of health and implementation science.
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Investigating the Role of Dopamine Circuits in Habit Formation
Scientists have uncovered how dopamine connects subregions of the striatum essential for habit formation, according to a Northwestern Medicine study.
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Protein Transformation Drives Cancer Development
A change in function in a mitochondrial protein is associated with gene expression that may promote the development of cancer, according to a recent Northwestern Medicine Study.
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Scientists Identify Key Mechanism Controlling Skin Regeneration
A new study has identified a molecular switch, through a protein called CDK9, that plays an early and critical role in the skin stem cell differentiation process.
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Scientists Discover Novel Cellular Mechanisms Behind Transcription Elongation
Northwestern Medicine investigators have discovered novel mechanisms underlying transcription elongation, the process of synthesizing RNA from DNA.
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‘Inside Out’ Signaling Promotes Tumor Growth
An immune system kinase promotes tumor inflammation and progression, according to a study published in Nature Communications.
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New Insights in Retinal Neurons
Northwestern Medicine investigators have identified a new type of retinal ganglion cell, neurons that encode the visual environment and transmit information back to the brain.
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Identifying Therapeutic Targets for Chemotherapy-Resistant Glioblastoma
Investigators have discovered novel cellular pathways behind chemotherapy-resistant glioblastoma cells and a potential biomarker, paving the way for new therapeutic targets.
