Category: Scientific Advances
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Study Identifies Distinct Roles for Nuclear Lamin Isoforms
A Northwestern Medicine study has uncovered distinct roles of major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics.
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Understanding Immunosuppressive Mechanisms of T-Cell Receptors
Investigators have discovered the mechanisms underlying a T-cell receptor’s immunosuppressive function, findings that may improve the development of precision therapeutics for chronic disease, including cancer.
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Mitochondrial Respiratory Chain Sustains Inflammation
A Northwestern Medicine study published in Nature Immunology has discovered that mitochondria control the activation of a specific protein complex linked to inflammation and the progression of chronic diseases.
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Identifying Mechanisms of Methylation in Stem Cells
Northwestern Medicine scientists identified critical regulatory processes that govern differentiation in embryonic stem cells.
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Mechanisms of Pregnancy-Associated Heart Growth Identified
Northwestern Medicine scientists have uncovered a key regulator of pregnancy-associated heart growth, according to a recent study published in the Journal of Clinical Investigation.
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Cytoskeletal Proteins Interact to Form Intracellular Networks
Investigators have discovered that two cytoskeletal proteins which were previously thought to function independently actually interact and form essential cytoskeletal networks within the cell surface.
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New Function for Glucose Metabolism Enzyme
The function of the mitochondrial enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study.
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Transcription Factors Cooperate to Promote Cancer Growth
A well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to a Northwestern Medicine study published in Science Advances.
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Exploring Flow Transport in Egg Cells
Motor proteins “slingshot” microtubules within developing egg cells of fruit flies, creating a current that transports mRNA to a developing egg.
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Proactive Machine Learning Could Speed Healthcare Innovation
Shifting machine learning workflows to a proactive model could speed data collection and analysis, according to a viewpoint published in JAMA.
