Category: Scientific Advances
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Genetic Variations Influence Drug Metabolism in Patients of African Descent
Northwestern Medicine investigators have identified new genetic variations effecting gene expression in the liver cells of patients of African descent, findings that provide insight into how drugs are metabolized differently in different populations.
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Longtime Alcohol Consumption Speeds Up Biological Aging
Consuming certain types of alcohol over long periods of time as well as binge drinking both speed up biological aging, according to a recent Northwestern Medicine study.
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Transforming the Way Cancer Vaccines are Designed and Made
A new way to significantly increase the potency of almost any vaccine has been developed by Northwestern scientists.
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Calcium Channels Regulate Neuroinflammation and Neuropathic Pain
Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain.
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Shortage of Mental Health Professionals Linked to Increase in Youth Suicides
Shortages of mental health professionals across U.S. counties were associated with an increase in youth suicides, according to a Northwestern Medicine study.
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Wireless Brain Implant Monitors Neurotransmitters in Real Time
Scientists have developed a wireless, battery-free implant capable of monitoring dopamine signals in the brain in real-time, an advance that could aid in understanding the role neurochemicals play in neurological disorders.
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Mature ‘Lab Grown’ Neurons Hold Promise for Neurodegenerative Disease
Northwestern scientists have created the first highly mature neurons from human induced pluripotent stem cells, a feat that opens new opportunities for medical research and potential transplantation therapies for neurodegenerative diseases.
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Study Uncovers Potential Therapeutic Approach for Advanced Prostate Cancer
A Northwestern Medicine study has discovered that elevated PALI1 in advanced prostate tumors mediates crosstalk between two primary epigenetic silencing mechanisms, suggesting that dual epigenetic inhibition may be an effective therapeutic strategy.
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Investigating Disparities in Machine Learning Algorithms
Integrating social determinants of health helped mitigate bias when predicting long-term outcomes for heart failure patients, according to a Northwestern Medicine study.
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Aging Is Driven by Unbalanced Genes
In a new study, Northwestern investigators used artificial intelligence to analyze data from a wide variety of tissues, and discovered that the length of genes can explain most molecular-level changes that occur during aging.
