Category: Disease Discoveries
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Northwestern Medicine Researchers Solve Mystery of Deadly Transplant Infection
Northwestern Medicine scientists have identified a specific bacteria that may be the cause of a rare lung infection that affects lung transplant patients.
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Structure of Parainfluenza Virus 5 Reveals How Replication Occurs
Northwestern Medicine scientists have for the first time, determined the protective structure of the parainfluenza virus 5 nucleocapsid ring, which hides the viral RNA genetic material from the outside environment. These findings may help to explain how the virus and other membrane-enveloped viruses including measles and mumps replicate with minimal changes to the protective ring[…]
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Tracking HIV to the Cell Nucleus
Northwestern Medicine scientists explored how HIV uses host factor FEZ-1 to move in cells to the nucleus.
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Pathway Signals Motor Neuron Death in Spinal Muscular Atrophy
Northwestern Medicine scientists have found a signaling pathway that contributes to motor neuron degeneration in spinal muscular atrophy, and may help to better understand other neurodegenerative disorders.
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Neighborhood Segregation Linked to Cardiovascular Disease
Higher neighborhood segregation is associated with a higher risk of cardiovascular disease for blacks and a lower risk for whites, according to a recent Northwestern Medicine study.
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Cancer Genes Turned Off in Deadly Brain Cancer
Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM) when delivered using spherical nucleic acid nanoparticles.
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White Matter Plays Big Role in Brain Injury Recovery
A new Northwestern Medicine study reveals that white matter loss is associated with impaired verbal abilities, an important implication for cognitive recovery following traumatic brain injury.
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‘Phenomapping’ Categorizes Heart Failure to Tailor Therapies
Northwestern Medicine scientists used “big data” tools to classify for the first time three distinct categories of a common heart failure syndrome. The findings may be used to better predict how diverse patients will respond to treatments.
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Targeting Growth Factor Improves Skin Cancer Therapies
A Northwestern Medicine study found that standard treatments for metastatic melanoma are not effective against Nodal, a growth factor protein critical for the skin cancer’s development, but also showed that combination therapies incorporating anti-Nodal antibodies are a promising alternative.
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Exploring Bacterial Competition in Reproductive Tract Infections
Northwestern Medicine scientists have shown that the bacteria that cause gonorrhea may have evolved mechanisms to stimulate white blood cells into killing other bacteria, promoting the survival of gonorrhea bacteria in the human reproductive tract.
