Category: Disease Discoveries
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Scientists Identify Genetic Drivers of Common Lymphoma
A team of scientists has identified the genetic drivers of diffuse large B-cell lymphoma, the most common type of blood cancer, and determined the genes’ clinical significance.
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Novel Technique Explains Herbicide’s Link to Parkinson’s Disease
Northwestern Medicine scientists have published a paper in Nature Chemical Biology, detailing an innovative use of CRISPR-Cas9 technology that has helped reveal how oxidative stress explains a common herbicide’s link to risk of Parkinson’s.
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New Insights Into Herpes Virus Could Inform Vaccine Development
Research published in Proceedings of the National Academy of Sciences provides new insights into antibodies that block the Epstein-Barr virus from infecting human cells.
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Previously Unknown Gene Mutation May Increase Risk for Heart Disease
A newly discovered gene mutation may increase a patient’s risk of genetic heart disease, presenting a target for therapy or genetic screening down the road.
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Students and Trainees Study the Immune System to Improve Heart Tissue Repair
Northwestern Medicine scientists have demonstrated the potential of targeting inflammatory pathways in order to limit tissue damage and improve repair after a heart attack.
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Toxic Genetic Material’s Origins Discovered
A Northwestern Medicine study found a novel chemical transformation in the formation of colibactin, a toxic agent produced by gut bacteria, including certain strains of E. Coli.
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HIV Infection Hijacks Intracellular Highways
A Northwestern Medicine study found the human immunodeficiency virus uses proteins called diaphanous-related formins to hijack the cytoskeleton of healthy cells.
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Scientists Discover Novel Mechanism Underlying ALS and Related Dementia
A study has identified a new mechanism for how a gene mutation leads to the death of neurons in amyotrophic lateral sclerosis and a related form of dementia.
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Brain Rewiring in Parkinson’s Disease May Contribute to Abnormal Movement
A study published in Neuron suggests the brain’s own compensatory mechanisms contribute to the debilitating motor symptoms of Parkinson’s disease.
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Genomic Analysis Offers Insights into Cause of Wilms Tumor
A comprehensive genomic analysis of the most common kidney cancer in children – found genetic mutations involving two distinct processes, potentially providing new opportunities for future treatments.
