Category: Disease Discoveries
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Understanding How Metabolism Contributes to Parkinson’s Disease
Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson’s disease, according to a study published in Nature Communications.
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Shared Pathways in HIV and Aging May Contribute to Heart Failure Risk
Scientists have discovered a unique proteomic signature expressed in the blood of persons living with HIV (human immunodeficiency virus) that is associated with age and higher risk for heart failure, findings that can help identify new therapeutic targets for heart failure among both people living with and without HIV.
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Investigating the Impact of Vaccination on Long COVID Symptoms
Vaccination status does not impact the severity of neurological symptoms of long COVID, according to a Northwestern Medicine-led study published in Brain Communications.
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Drug Reverses Groin Hernias in Male Mice Without Surgery, Shows Promise in Humans
A new Northwestern Medicine study using a novel medication-based approach successfully reversed existing inguinal hernias in male mice and fully restored their normal anatomy without surgery.
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Investigating New Treatments for Rare Skin Lymphomas
A fusion protein therapy may be an effective treatment option for cutaneous T-cell lymphomas, according to a multicenter clinical trial published in the Journal of Clinical Oncology.
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Redefining Obesity With New Global Guidelines
An international team of scientists has developed a new set of global clinical guidelines for obesity aimed at better diagnosing and categorizing the condition, according to a report published in The Lancet Diabetes and Endocrinology.
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Exploring Genetic Sex Differences in Alzheimer’s
An international team of scientists has uncovered new insights into how previously unstudied X chromosomes in women may contribute to Alzheimer’s Disease risk, according to a multicenter study published in the journal Molecular Psychiatry.
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Novel Approach Pinpoints Genetic Variants Linked to Parkinson’s Disease Risk
Investigators have developed a novel approach that can better identify genetic variant interactions that are associated with increased risk of Parkinson’s disease, according to a recent study published in Brain.
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Potential Therapeutic Target for Ischemic Acute Kidney Injury Discovered
Investigators led by Pinelopi Kapitsinou, MD, have discovered that inhibiting the hypoxia-driven MCT4 protein in kidney endothelial cells may halt the progression of ischemic acute kidney injury to chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
