Category: Disease Discoveries
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Study Identifies Gene Linked to Rare Ciliopathy Disorders
A Northwestern Medicine-led study has identified mutations in the gene CEP76 as a new cause of ciliopathies, shedding light on a complex group of disorders that affect multiple body systems, according to a study published in Science Advances.
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Transcription Factor Drives Chemotherapy Resistance in Ovarian Cancer
Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and chemotherapy resistance in ovarian cancer cells, findings that may inform new targeted treatment approaches that inhibit this process and improve patient outcomes, according to a recent study published in The Journal of Clinical Investigation.
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Childhood Blood Pressure Holds Clues for Lifelong Heart Health
Blood pressure measured as early as age seven can predict cardiovascular mortality decades later, according to a new Northwestern Medicine study published in JAMA.
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Patient Wealth is Associated with Quality of Glaucoma Care
Patients with newly diagnosed glaucoma who have less wealth or reside in rural communities are less likely to receive standard glaucoma care compared to wealthier patients, according to a recent multi-institution study published in JAMA Ophthalmology.
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Carbon Dioxide May Drive Lung Damage in COPD
A new Northwestern Medicine study is challenging long-held assumptions about chronic obstructive pulmonary disease (COPD), according to results published in The Journal of Clinical Investigation.
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Investigating How Tumor-Immune Cell Clusters Drive Cancer Spread
In a pair of studies, investigators from the lab of Huiping Liu, MD, PhD, have uncovered how specific cellular interactions in the bloodstream may be fueling the spread of breast cancer.
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Surge in Rare Pediatric Brain Disorder Linked to Flu Season
A surge in a rare but devastating brain disorder in children has been linked to the 2024-2025 flu season, according to a nationwide study published in JAMA.
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Molecular Mechanisms Support Long-term Immunity
Scientists in the laboratory of Weiguo Cui, PhD, have identified novel molecular mechanisms that help specialized T-cells maintain long-term immunity in response to chronic infection and cancer, according to recent findings published in Nature Immunology.
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Study Explores Diet’s Significant Role in Global Obesity
An international multi-center study revealed how diet plays a greater role in the prevalence of obesity globally than was previously understood, according to findings published in the Proceedings of the National Academy of Sciences.
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Study Reveals Surprising Link Between HIV and Alzheimer’s
A new Northwestern Medicine study has uncovered a surprising molecular link between HIV-1 and a protein fragment associated with Alzheimer’s disease, according to findings published in the Proceedings of the National Academy of Sciences.
