Category: Disease Discoveries
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Glioblastoma Survival Mechanism Reveals New Therapeutic Target
A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.
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Scientists Investigate Protein’s Role in Lupus Development
A new Northwestern Medicine study suggests that a protein called Bim may be a novel therapeutic target for lupus.
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Delayed Development of Fast-Spiking Neurons Linked to Fragile X
Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a neurodevelopmental disorder.
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Blocking Gene Expression Improves Outcomes in Blood Disease in Models
Scientists reduced blood clotting in mice with a blood disease called myeloproliferative neoplasm by inhibiting expression of a gene.
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New Insights Into Protein Reveal Potential Therapy for Breast Cancer
Northwestern Medicine scientists have uncovered new findings about a protein called SET1B, which could offer a novel approach to treating triple-negative breast cancer.
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Exploring the Genetics of Glaucoma and Retinal Development
Northwestern Medicine scientists have discovered a genetic basis for glaucoma symptoms and the impact of other genes in early retinal development.
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Crystal Structures Reveal How Abnormal Protein Interactions Impair Synapse Function
Northwestern Medicine investigators applied discovery-based proteomics to identify synaptic protein interactions that possibly contribute to autism spectrum disorders.
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Scientists Identify Genetic Drivers of Common Lymphoma
A team of scientists has identified the genetic drivers of diffuse large B-cell lymphoma, the most common type of blood cancer, and determined the genes’ clinical significance.
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Novel Technique Explains Herbicide’s Link to Parkinson’s Disease
Northwestern Medicine scientists have published a paper in Nature Chemical Biology, detailing an innovative use of CRISPR-Cas9 technology that has helped reveal how oxidative stress explains a common herbicide’s link to risk of Parkinson’s.
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New Insights Into Herpes Virus Could Inform Vaccine Development
Research published in Proceedings of the National Academy of Sciences provides new insights into antibodies that block the Epstein-Barr virus from infecting human cells.
