Category: Disease Discoveries
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New Genes Implicated in Multiple System Atrophy
A large international team of scientists have uncovered genetic risk factors for multiple system atrophy, according to a study published in Neuron.
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Gene Therapies Could Transform Treatment of Rare Blood Disorders
A new gene therapy could revolutionize treatment for two rare genetic blood disorders, according to a pair of trials published in the New England Journal of Medicine.
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New Mechanisms Underlying Tumor Variety in Brain Cancers Discovered
Investigators have discovered new mechanisms underlying intratumor heterogeneity and treatment resistance in meningiomas, the most common type of primary central nervous system tumor, according to a recent study published in Nature Genetics.
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Novel Genetic Mechanisms May Serve as Therapeutic Target Against Glioma
A recent study from the laboratory of Shi-Yuan Cheng, PhD, has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in The Journal of Clinical Investigation.
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Genetic Variation Linked to Increased Risk of Pick’s Disease
A unique genetic variation in the MAPT gene was associated with increased risk of Pick’s disease, a rare form of frontotemporal dementia, according to a recent study published in The Lancet Neurology.
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Leading Prostate Cancer Research for More than 20 Years
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center…
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B-Cells May Play Role in Lung Transplant Rejection
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation that can lead to rejection, according to a study published in the Journal of Clinical Investigation.
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Study Discovers Potential Biomarkers of Environmental Exposures in Parkinson’s Disease
A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson’s disease, findings that demonstrate the potential for using DNA methylation as a biomarker to identify the disease.
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Uncovering the Culprits of Neurodegenerative Disorders
Recent studies from Feinberg scientists have uncovered new insights into these disorders, elucidating the mechanisms behind Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis, or ALS.
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Potential Therapeutic Target for Small Cell Lung Cancer Discovered
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer cells may decrease cancer cell differentiation and tumor growth, according to findings published in Nature Communications.
