Category: Disease Discoveries
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Scientists Discover a Cause of Lupus and a Possible Way to Reverse It
Scientists have discovered a molecular defect that promotes the pathologic immune response in lupus and demonstrated that reversing the defect may potentially reverse the disease.
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Intracellular Mechanisms Promote Spread of Deadly Bacterial Infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in Proceedings of the National Academy of Sciences.
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Blood Test Could Provide Snapshot of Overall Health
Circulating protein levels may serve as a biomarker for cardiorespiratory fitness, an important but previously hard-to-measure component of overall health, according to a study published in Nature Medicine.
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B Vitamins May Help Those with Artery Disease Walk Farther
Vitamin B3 supplements may help people with peripheral artery disease walk farther, according to a Northwestern Medicine-led clinical trial published in Nature Communications.
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New Cellular Mechanisms in Parkinson’s Disease Discovered
A pair of recent studies led by Joseph Mazzulli, PhD, have uncovered previously unknown cellular mechanisms involved in neuronal protein aggregation and misfolding, key characteristics of Parkinson’s disease, which may serve as therapeutic targets.
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Embryo’s Signaling Mechanism May Promote Healthy Aging, Combat Neurodegenerative Diseases
Northwestern investigators have identified a novel transcription factor which regulates a signaling mechanism utilized by a fertilized embryo to protect its mother from cellular and environmental stress, according to a recent study to published in the journal Genes and Development.
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Understanding Inflammation in the Heart
Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
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Weakened Virus Helps Eliminate Cancer
Northwestern Medicine scientists have discovered that a weakened form of a virus can be used to help eliminate cancer in mice.
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Dysfunctional Enzyme May Lead to Liver Disease
A dysfunctional enzyme may lead to nonalcoholic fatty liver disease in mice, according to a study published in Science Advances.
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Regenerating Damaged Heart Cells
Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects, according to a study published in the Journal of Clinical Investigation.
