Category: Disease Discoveries
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Modifier Genes Modulate Inherited Cardiac Disorder
Investigators found two genes that modulate the severity of Long QT Syndrome, an inherited cardiac disorder that can cause heart arrhythmias and sudden death.
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Immune Response May Contribute to Pediatric Epilepsy
Immune cells migrating from the bloodstream to the brain may contribute to seizures in pediatric epilepsy, according to new findings published in the Journal of Experimental Medicine.
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Chemotherapy Drug Shows Promise in Treating Everyday Allergies
A drug originally designed for chemotherapy may reduce allergic responses for a variety of allergens, according to a study published in the Journal of Allergy and Clinical Immunology.
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Huntington’s Disease Provides New Cancer Weapon
Northwestern Medicine scientists have discovered why Huntington’s disease is so toxic to cancer cells and have harnessed it for a novel approach to treat cancer.
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Rare Melanoma Shows Sensitivity to Immune Therapy
Antibodies that reverse immune system suppression may be able to be used to treat a rare type of melanoma, according to a Northwestern Medicine study published in the journal Nature.
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Mechanism Behind Autoimmune Disorder Revealed
The previously unknown cause of anti-phosphatidylethanolamine (aPE) autoimmunity was discovered in a Northwestern Medicine study published in PNAS.
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Mechanism Behind Common Parkinson’s Mutation Discovered
Northwestern Medicine scientists uncovered the molecular process behind a buildup of toxic proteins in Parkinson’s patients, a discovery that may lead to improved therapies.
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Testosterone-linked Molecule Explains Gender Differences in MS
Northwestern Medicine scientists have identified a guardian molecule triggered by testosterone that appears to protect males from multiple sclerosis.
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Genetic Basis Uncovered for Glaucoma
Northwestern Medicine scientists have discovered mutations that cause improper drainage and a buildup of ocular pressure leading to glaucoma, suggesting a path towards future treatments.
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PhD Student Explores Role of Exosomes in Cancer Metastasis
Northwestern Medicine scientists have demonstrated that tiny vesicles called exosomes released from non-metastatic melanoma cells trigger an immune response that prevents cancer from spreading throughout the body.
