Category: Disease Discoveries
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New Developments in Quest for Huntington’s Disease Treatments
A molecule drastically reduced toxic proteins in human neuron cells with Huntington’s disease, representing a potential therapy for the deadly degenerative disease, according to a new study.
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Exploring the Molecular Mechanisms of Ion Channels and Kidney Disease
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
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Targeting a Weak Link in Pediatric Brain Cancer
A new study has found that a particularly deadly form of pediatric brain tumor may have a weakness that could inspire future treatments.
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New Insights Into Role of RNA Methylation in Fragile X Syndrome
Northwestern Medicine scientists have discovered that the protein FMRP — the loss of which leads to Fragile X syndrome — is a novel reader of RNA methylation.
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Pancreatic Cancer Drug, High-Fat Diet Linked to Liver Disease Risk
An emerging class of cancer drugs has shown promise in treating pancreatic cancer, but the drugs may cause severe liver damage when combined with high-fat diets, according to study published in PNAS.
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Subclinical Macular Degeneration Requires Monitoring
A new Northwestern Medicine study published in PLOS One affirmed the importance of monitoring patients with age-related macular degeneration to ensure their disease does not progress further.
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Mitochondrial Defects Contribute to Muscular Disease
A new study published in Developmental Cell discovered a link between a previously unknown mitochondrial process and Charcot-Marie-Tooth disease Type 2, a genetic neuropathy.
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Exercising to Improve Function in Muscular Dystrophy
Low- and moderate-intensity exercise improved muscle, heart and breathing function in an animal model of Duchenne muscular dystrophy, according to a Northwestern Medicine study.
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Protein Quality Control Falters in Neurodegenerative Disease
Northwestern scientists have discovered how certain genetic mutations can weaken protein “quality control,” identifying a pathway that may contribute to neurodegenerative diseases.
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Mutations Synergize in Pediatric Brain Cancer
A new Northwestern Medicine study has demonstrated that a combination of two mutations makes a form of pediatric brain tumors more deadly.
