Category: Disease Discoveries
-
Secondary Bacterial Pneumonia Drove Many COVID-19 Deaths
Secondary bacterial pneumonia that did not resolve was a key driver of death in patients with COVID-19, according to a recent study in the Journal of Clinical Investigation.
-
Uncovering the Causes of Neuron Dysfunction in Huntington’s Disease
Investigators led by D. James Surmeier, PhD, the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington’s disease.
-
Study Identifies Enzyme that Helps Tumors Evade the Immune System
Northwestern Medicine scientists have identified an enzyme which aids tumors in evading the immune system, findings that could provide future directions for tumor treatment, according to a study published in Nature Communications.
-
New Therapy Harnesses Patients’ Blood Cells to Fight Tumors
Northwestern University scientists have discovered it is possible to isolate a tumor’s attack cells non-invasively from blood, rather than from tumors.
-
The Future of IgE-Mediated Allergy Research and Treatments
In a recent editorial published in the Journal of Experimental Medicine, Cecilia Berin, PhD, discusses the current state of IgE-mediated food allergy treatments, targeting type 2 immune responses, and next steps for food allergy research and treatment development.
-
Sex-Specific Mechanisms for Major Depressive Disorder Identified in Response to Dysregulated Stress Hormones
Northwestern Medicine investigators have discovered novel sex-specific mechanisms that control how stress hormones impact dopamine transmission and motivation, findings that can inform new therapeutic strategies for treating major depressive disorder.
-
Studying the Impact of Stem Cell Transplants
People with sickle cell disease who receive nonmyeloablative stem cell transplants are at greater risk for developing new tumors, according to a new study published in the Journal of Clinical Oncology.
-
Social Deficits and Seizures in Autism Type Tied to Overexcited Brain Circuits
Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.
-
Calming the Destructive Cells of ALS by Two Independent Approaches
Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS.
-
Potential Therapeutic Target for Blood Cancers Discovered
Investigators have discovered that a specific complex drives cell proliferation in mutated myeloproliferative neoplasms, suggesting this complex could serve as an ideal therapeutic target, according to a recent Northwestern medicine study.
