Category: Disease Discoveries
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New Treatment Directions for Rare Brain Disorder
A Northwestern Medicine study has uncovered a promising new therapeutic approach for a rare genetic brain disorder, according to findings published in Nature Communications.
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Post-Stroke Injection Protects the Brain in Preclinical Study
Northwestern University scientists have developed an injectable regenerative nanomaterial that helps protect the brain during the vulnerable window after a patient suffers a stroke.
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Investigating HIV’s Hidden Immune Evasion Strategy
A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding detection.
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Tanning Beds Triple Melanoma Risk, Potentially Causing Broad DNA Damage
Tanning bed use is tied to almost a threefold increase in melanoma risk, and for the first time, scientists have shown how these devices cause melanoma-linked DNA damage across nearly the entire skin surface, according to a recent study.
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Hypervigilance, Anxiety Linked to Poor Treatment Outcomes in Esophageal Disorder
Increased esophageal hypervigilance and anxiety were associated with worse post-treatment symptoms and poor quality of life in patients with achalasia, a rare esophageal motility disorder, according to a recent Northwestern Medicine study.
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Targeting Aberrant Learning May Improve Parkinson’s Treatment
Northwestern Medicine scientists have discovered that targeting neuronal signaling controlling aberrant learning in the striatum may improve the efficacy of a first-line therapy for Parkinson’s disease and has the potential to reduce therapy-related side effects, according to a recent study published in Science Advances.
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Shape-Shifting Cell Channel Reveals New Target for Precision Drugs
In a new study published in Nature Communications, Northwestern scientists have uncovered how a critical membrane pathway controls the flow of chemical messages responsible for everything from brain activity to inflammation.
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NU-9 Halts Alzheimer’s Disease In Animal Model Before Symptoms Begin
In a new study, scientists have identified a previously unknown driver of Alzheimer’s disease, and an experimental drug developed at Northwestern University has demonstrated further promise as an early intervention to treat the disease.
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Common Virus ‘Rewires’ Intracellular Mechanisms to Promote Infection
Investigators from the laboratory of Derek Walsh, PhD, have discovered how human cytomegalovirus rewires intracellular mechanisms to control the movement of the cell nucleus and promote infection, according to a recent study.
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RNA ‘Quality Control’ System Breaks Down in ALS
A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS), according to findings published in the journal Neuron.
