Category: Clinical Breakthroughs
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AI Models Predict Sepsis in Children, May Enable Preemptive Care
Northwestern scientists have developed and validated AI models that accurately identify children at high risk for sepsis within 48 hours, so they can receive early preemptive care.
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Nearly Everyone Has at Least One Risk Factor Before a Heart Attack, Stroke or Heart Failure
More than 99 percent of people who went on to suffer a heart attack, stroke or heart failure already had at least one risk factor above optimal level beforehand, according to a new study.
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Black Adults Face Heart Failure Nearly 14 Years Earlier than White Patients
Black adults in the U.S. are first hospitalized for heart failure nearly 14 years earlier than white adults, according to a new study analyzing data from more than 42,000 patients across hundreds of hospitals.
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Diabetes Drug May Protect Against Kidney Inflammation
A new study has shed light on how a class of diabetes drugs may protect the kidneys — not just by lowering blood sugar, but by triggering a molecular shift that dampens inflammation, according to the study published in The Journal of Clinical Investigation.
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Identifying Biomarkers to Guide Prostate Cancer Treatment
Biological markers may help predict which patients will benefit most from specific therapies to treat prostate cancer, according to a study published in the journal Cell.
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Modified T-cells Promote Tissue Repair from Pneumonia
Northwestern Medicine scientists have discovered that a subset of laboratory-modified T-cells can promote the repair of lung tissue damaged by viral pneumonia, according to a recent study published in The Journal of Clinical Investigation.
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Novel Monoclonal Antibody May Improve Sepsis Treatment
A novel monoclonal antibody treatment developed in collaboration with Northwestern Medicine scientists reduced inflammation and immune dysregulation in mouse models of sepsis, underscoring the antibody’s therapeutic potential in treating the disease, according to a recent study.
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Wearable Sensors Could Reshape Obesity Treatment
Northwestern scientists have created a new lifestyle medicine program that uses three wearable sensors to capture real-world eating behavior in unprecedented detail.
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Timely Pain Treatment Linked to Reduced Hospitalizations for Children with Sickle Cell Disease
A new study has found that prompt administration of opioid pain relief in emergency departments reduces the likelihood of hospitalization for children with sickle cell disease, according to findings published in JAMA Pediatrics.
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Investigating New Treatments for Spinal Muscular Atrophy
A new clinical trial has revealed encouraging results for a muscle-targeting therapy aimed at improving motor function in children and adolescents with spinal muscular atrophy, according to a study published in The Lancet Neurology.
