Category: Clinical Breakthroughs
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Time-Restricted Eating Supports Weight Loss in Women with PCOS
A time-restricted eating program promoted greater weight loss in women with polycystic ovary syndrome (PCOS) than no intervention, according to a randomized controlled trial published in Nature Medicine.
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Nonsurgical Heart Valve Replacement Improves Patient Outcomes
Patients with severe heart valve disease who underwent nonsurgical transcatheter tricuspid valve replacement showed significant improvements in overall cardiovascular health status and quality of life within 30 days post procedure, according to a recent study published in JAMA.
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New U.S. Estimates of Sepsis in Kids Point to Urgent Need to Reduce High Mortality Rates
New estimates of rates of sepsis during pediatric hospitalizations have been obtained by a multicenter team of investigators, using clinical data from electronic health records.
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Stents Can Ease Symptoms of Post-Thrombotic Syndrome
A procedure designed to reopen blocked veins successfully reduced pain, swelling and disability in people with post-thrombotic syndrome — a common and often debilitating complication of deep vein thrombosis — according to results of a clinical trial published in The New England Journal of Medicine.
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Little-Used Cholesterol Test Could Prevent More Heart Attacks, Strokes
A new Northwestern Medicine study published in JAMA has found that a little-used cholesterol test outperformed standard tests in guiding cholesterol-lowering therapy.
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New Drug Doubles One-Year Survival in Pancreatic Cancer Trial
Patients who received an experimental drug developed at Northwestern University alongside standard chemotherapy were twice as likely to be alive after one year of treatment, compared to those receiving chemotherapy alone.
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Experimental Drug Lowers Parkinson’s-Linked Protein in Early Trial
An experimental drug designed to silence a gene strongly linked to Parkinson’s disease has shown encouraging effects in a first-in-human clinical trial, according to a study published in Nature Medicine.
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Policy Intervention Linked to Increase in Kidney Transplants in Black Patients
A national policy intervention implemented to address transplant inequities caused by race-based kidney function equations was associated with an increase in organ transplant rates among Black patients, according to a recent study published in JAMA Internal Medicine.
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Bariatric Surgery in Adolescents ‘Reprograms’ Kidney Biology to Promote Recovery
Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms that may serve as potential targets for non-surgical treatments for diabetic kidney disease, according to a multi-institutional study published in The Journal of Clinical Investigation.
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FDA-Approved Compound Promotes Neuroprotective Effects in Parkinson’s Disease
Northwestern Medicine scientists have discovered an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson’s disease, according to a recent study published in The Journal of Clinical Investigation.
