Byline: Melissa Rohman
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Transcription Factor Drives Chemotherapy Resistance in Ovarian Cancer
Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and chemotherapy resistance in ovarian cancer cells, findings that may inform new targeted treatment approaches that inhibit this process and improve patient outcomes, according to a recent study published in The Journal of Clinical Investigation.
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Novel Molecular Mechanisms Shape Neuron Identity
A recent study led by Tiffany Schmidt, PhD, has discovered previously unknown cellular mechanisms that shape neuron identity in retinal cells, findings that may improve the understanding of brain circuitry and disease.
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Uncovering New Therapeutic Targets for Cancer Mutations
A team of Northwestern investigators has discovered novel molecular underpinnings of a common oncogenic mutation in cancer, findings that may inform the development of new therapeutic strategies, according to findings published in Nature Chemical Biology.
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Obesity Drugs Regulate Neural Systems to Curb Appetite
Lisa Beutler, MD, PhD, assistant professor of Medicine in the Division of Endocrinology, Metabolism and Molecular Medicine, was senior author of the study published in The Journal of Clinical Investigation.
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Spearheading Reproductive Science Research
In 1974, Neena Schwartz, PhD, the William Deering Professor of Endocrinology, launched Northwestern’s Program for Reproductive Research to catalyze reproductive biology research and collaboration across the university.
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Bass Elected to the National Academy of Medicine
Joseph Bass, MD, PhD, the Charles F. Kettering Professor of Medicine, has been elected to the National Academy of Medicine for his foundational work in expanding the field of circadian mechanisms in metabolic health and disease.
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Minimally Invasive Surgery May Improve Outcomes in Severe Stroke
Minimally invasive endoscopic surgery may be an effective and safe treatment for patients with intracerebral hemorrhage, the most severe type of stroke, according to results from a recent clinical trial published in JAMA Neurology.
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New Ultrasound Curricula May Improve Residency Education and Training
New consensus-based recommendations on point-of-care ultrasound skills, instructional methods, and assessment strategies could help improve ultrasound education and training nationwide, as detailed in a recent study published in Annals of Internal Medicine.
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Goyal Named Mallinckrodt Foundation Grant Fellow
Yogesh Goyal, PhD, assistant professor of Cell and Developmental Biology, has been named a 2025-2028 Edward Mallinckrodt, Jr. Foundation Grant Fellow, which recognizes early-stage biomedical investigators engaged in basic and translational research that has the potential to make fundamental advances in biomedical science.
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Subgroups of Interneurons Regulate Learning and Fear Responses
Northwestern Medicine investigators have uncovered new insights into the synaptic connections of subgroups of interneurons, findings that may improve the understanding of fear responses and could inform new targeted therapies for post-traumatic stress disorder (PTSD), according to a recent study.
