Byline: Melissa Rohman
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Transcription Factors Form Continuous ‘Circuit’ That Regulates T-cell Exhaustion
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic strategies for managing infections and cancer, according to a recent Northwestern Medicine study.
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Policy Intervention Linked to Increase in Kidney Transplants in Black Patients
A national policy intervention implemented to address transplant inequities caused by race-based kidney function equations was associated with an increase in organ transplant rates among Black patients, according to a recent study published in JAMA Internal Medicine.
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Uncovering Cellular Drivers of Increased Brain Signal Activity
Northwestern Medicine scientists have discovered new insights into how high gamma activity, a widely studied brain signal, is generated, findings that can impact how past and future neurological studies using this signal are interpreted, according to a recent study published in Nature.
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Study Identifies New Molecular Mechanisms Supporting Cell Adhesion
Scientists led by Sergey Troyanovsky, PhD, professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process disrupted in a variety of skin and inflammatory diseases, according to a recent study published in the Journal of Cell Biology.
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Light Impacts How the Brain Perceives and Remembers Threats
Northwestern Medicine scientists have discovered that light plays a key role in how animals perceive environmental threats, findings that could improve the understanding of risk avoidance behaviors and disorders in humans, according to a recent study published in Nature Communications.
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Fructose Uptake in Immune Cells Promotes Glioblastoma Growth
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor microenvironment metabolize fructose to suppress immune responses and promote tumor growth, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Bariatric Surgery in Adolescents ‘Reprograms’ Kidney Biology to Promote Recovery
Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms that may serve as potential targets for non-surgical treatments for diabetic kidney disease, according to a multi-institutional study published in The Journal of Clinical Investigation.
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FDA-Approved Compound Promotes Neuroprotective Effects in Parkinson’s Disease
Northwestern Medicine scientists have discovered an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson’s disease, according to a recent study published in The Journal of Clinical Investigation.
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Calcium Signaling Channels Regulate Neuroinflammation and Motivation
Northwestern Medicine scientists have discovered how calcium signaling channels in the brain’s immune cells regulate neuroinflammation and promote the development of behaviors associated with affective mood disorders, according to a recent study published in Science Signaling.
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Automated Screening and Education Increases Urinary Incontinence Diagnoses
Implementing an automated urinary incontinence screening and educational program in primary care practices significantly increased awareness and treatment referrals in women with the condition, according to a recent study published in JAMA Internal Medicine.
