Byline: Melissa Rohman
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Successful Gene Editing Demonstrated for a Rare Neurodevelopmental Disorder
Scientists have implemented a novel gene-editing approach that may be an effective treatment for alternating hemiplegia of childhood (AHC), a rare neurodevelopmental disorder in children, according to a recent study published in Cell.
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Combination Approach May Improve Cancer Treatment Efficacy
Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according to a recent Northwestern Medicine study published in Science Advances.
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Mitochondria Support T-cells Proliferation and Memory Formation
Investigators led by Navdeep Chandel, PhD, have discovered how mitochondrial metabolism supports T-cell proliferation and also prevents T-cell exhaustion in cancer and chronic infection, according to a recent study published in Nature Immunology.
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New Molecular Mechanisms of Ovarian Aging Discovered
Investigators led by Francesca Elizabeth Duncan, PhD, have discovered new molecular mechanisms that enable specialized immune cells to cause ovarian aging and functional decline, according to a recent study published in PLOS Biology.
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New Tool Predicts Cardiovascular Disease Risk More Accurately
A new risk prediction tool developed by the American Heart Association (AHA) estimated cardiovascular disease (CVD) risk in a diverse patient cohort more accurately than current models, according to a recent study published in Nature Medicine.
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Novel Molecular Mechanisms Inform Targeted Therapies for Chronic Kidney Disease
A recent Northwestern Medicine study has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common type of polycystic kidney disease, according to findings published in Proceedings of the National Academy of Sciences.
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Gestational Diabetes May Signal Poor Prepregnancy Cardiovascular Health
Poor prepregnancy cardiovascular health is associated with a higher risk of developing gestational diabetes and coronary artery calcium in midlife, according to a recent Northwestern Medicine study.
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Investigating Nationwide IV Shortages After Hurricane Helene
Intravenous fluid use in pediatric emergency departments decreased nationwide following Hurricane Helene, according to a recent Northwestern Medicine study, findings that may help emergency departments better allocate resources.
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Diabetes Drug May Serve as Alternative Treatment Option for Hydrocephalus
A drug commonly used to treat diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, according to a study published in the Journal of Clinical Investigation.
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AI Imaging Approach May Help Identify Parkinson’s Sooner
An artificial intelligence-based imaging approach may be an effective tool for distinguishing patients with Parkinson’s disease from those with other closely related diseases sooner than current methods, according to a recent study published in JAMA Neurology.
