Investigators have demonstrated how molecular profiling of tumors can be used to help predict treatment response and survival in patients with meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Medicine.
A combination therapy improved progression-free survival in patients with metastatic castration-resistant prostate cancer with genetic mutations compared to either therapy alone or sequentially, according to results from a Northwestern Medicine-led clinical trial.
Northwestern Medicine investigators have identified distinct T-cell responses associated with patient outcomes in unvaccinated individuals with severe SARS-CoV-2 pneumonia, according to findings published in Nature Immunology.
An international team of investigators have discovered that oligodendrocytes contribute approximately one-third of plaque formation alongside neurons in mouse models of Alzheimer’s disease, according to a recent study published in Nature Neuroscience.
Investigators have discovered that aberrant activation of a specific oncoprotein drives key tumor promoting changes in the prostate tissue microenvironment during cancer progression, according to a Northwestern Medicine study published in Nature Communications.
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
Get to know Steven P. Cohen, MD, who recently joined Northwestern University Feinberg School of Medicine as the inaugural Edmond I. Eger Professor of Anesthesiology and vice chair of Research and Pain Medicine.
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
High-intensity exercise does not increase the risk of sudden cardiac death in individuals with congenital long-QT syndrome, a genetic heart disorder, according to findings from a recent study published in Circulation.
Northwestern Medicine investigators have discovered that uterine serous carcinoma tumors in Black patients express more aggressive and immunosuppressive features than tumors in white patients, according to a recent study published in the Proceedings of the National Academy of Sciences.
