Patients with a subtype of glioblastoma who received a combination treatment of a PARP inhibitor and standard chemotherapy did not demonstrate improved survival compared to chemotherapy and placebo, according to a recent clinical trial published in JAMA Oncology.
Long-term treatment with the drug upadacitinib significantly improved symptoms and quality of life compared to placebo in adolescents with moderate to severe atopic dermatitis after 76 weeks with strong evidence of safety, according to a recent Northwestern Medicine analysis of three international, randomized clinical trials.
Treatment with endovascular thrombectomy did not significantly improve outcomes after 90 days in patients with a large core stroke, as compared to patients who received standard stroke care alone, according to a recent clinical trial published in JAMA.
Targeting a specific neural circuit through noninvasive neuromodulation may reduce symptoms in patients with posttraumatic stress disorder (PTSD), according to a recent study published in Nature Neuroscience.
Investigators from Feinberg School of Medicine and fellow academic and research institutions celebrated the 100-year anniversary of The Journal of Clinical Investigation during a day-long symposium in the Hughes Auditorium on October 18.
Northwestern Medicine investigators have created a novel blood test that identifies adults who may be at increased risk of developing severe respiratory illnesses, according to a recent study published in the American Journal of Respiratory and Critical Care Medicine.
Northwestern Medicine investigators have discovered that a novel combination treatment promotes cancer cell death and tumor regression in mouse models of pancreatic cancer, providing a rationale for testing in future clinical trials, according to recent findings.
Investigators have discovered that targeting specific mechanisms linked to lipid metabolism in immune cells within tumors may improve response to current and future cancer immunotherapies, according to a recent study published in the journal Immunity.
Northwestern has established the Denning Ataxia Center, a multidisciplinary hub dedicated to improving the understanding of ataxia through integrating leading-edge research with patient-centered clinical care, with the goal of unraveling the complexities of the condition and developing improved treatments.
Northwestern Medicine scientists have discovered a new underlying mechanism that controls a specialized group of T-cells, findings that may serve as potential targets for treating inflammatory diseases and cancer, according to a recent study.