Author: mrr5831
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Novel Mechanism Eliminates ‘Bad’ Enzyme During Gene Expression
Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates ‘bad’ transcriptional elongation enzymes during gene expression, findings that may inform the understanding of adrenal diseases, according to a recent study published in Science Advances.
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Transcription Factor Binding Sites May Help Explain Underlying Causes of Many Diseases
Investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, findings that may improve the understanding of underlying causes of developmental disorders and cancer, according to a recent study.
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Mitochondria May Be a Promising Therapeutic Target for Inflammatory Diseases
Northwestern scientists have discovered how mitochondria influence the body’s immune response through modulating specific cell signaling pathways, according to a recent study published in Science Advances.
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Novel ‘Scaffolding’ Biomaterial Improves Bladder Regeneration and Function
A team of Northwestern scientists have developed a novel “scaffolding” biomaterial that improves bladder tissue regeneration and overall function better than current techniques.
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Novel Approach Pinpoints Genetic Variants Linked to Parkinson’s Disease Risk
Investigators have developed a novel approach that can better identify genetic variant interactions that are associated with increased risk of Parkinson’s disease, according to a recent study published in Brain.
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Potential Therapeutic Target for Ischemic Acute Kidney Injury Discovered
Investigators led by Pinelopi Kapitsinou, MD, have discovered that inhibiting the hypoxia-driven MCT4 protein in kidney endothelial cells may halt the progression of ischemic acute kidney injury to chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
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Novel Technique May Accelerate Study of Gene Regulation
Investigators from the laboratory of Ali Shilatifard, PhD, have developed a novel technique to precisely and efficiently study gene regulation, which may accelerate the development of new therapeutic strategies, according to a recent study published in Molecular Cell.
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Active Surveillance of Prostate Cancer On the Rise
The use of active surveillance and watchful waiting increased from 13.2 percent in 2010 to 53.8 percent in 2020 among patients with intermediate-risk prostate cancer, according to a recent study published in JAMA.
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Blood Test May Reduce Unnecessary Prostate Cancer Biopsies
A new blood test may help reduce unnecessary prostate biopsies and can detect prostate cancer with similar sensitivity to standard screening in patients across racial and ethnic groups, according to a recent study published in the Journal of Clinical Oncology.
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Global Health Day Highlights International Collaboration and Health Systems Improvement
Northwestern investigators, faculty, students and community partners shared and celebrated global health research, education and outreach during the 13th annual Global Health Day organized by the Robert J. Havey, MD Institute for Global Health, held on December 6.
