Tag: Research
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New Strategy Doubles Chemo Effectiveness in Treatment-Resistant Cancer
Northwestern scientists have discovered that the organization of a cell’s genetic material dictates cancer’s ability to adapt, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Cell Feature Implicated in Cancer Forms Differently than Previously Thought
A team lead by Northwestern scientists has found that paraspeckles, found in the nucleus of many cells, form differently than previously thought, which may aid in the design of future cancer drugs.
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Exploring the Role of Non-Coding RNA in Gene Regulation
A new study has revealed that a long non-coding RNA plays a far more extensive role in regulating gene expression than previously understood, according to findings published in Nature Communications.
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Developing Tools for Studying Essential Genes in Real Time
Northwestern Medicine investigators have developed a powerful new tool that allows scientists to precisely and rapidly control protein levels in living cells—offering unprecedented insight into the inner workings of essential genes, according to a new study published in Nature Communications.
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How a ‘DNA Detangler’ Gene Protects Against Blood Cancer
A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that may lead to leukemia, according to findings published in Nature Communications.
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Revealing Hidden Drivers of Asthma Flare-Ups in Children
A multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.
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New Wireless Sweat Patch May Improve Cystic Fibrosis Treatment
A new wireless and wearable device developed by Northwestern Medicine scientists measures specific biomarkers in a person’s sweat and has the potential to improve clinical decision-making for cystic fibrosis, as detailed in a recent study published in the Proceedings of the National Academy of Sciences.
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New Drug Shows Promise in Treating a Common Cause of Hypertension
A novel drug may significantly improve outcomes for a subset of patients with high blood pressure, according to findings published in The New England Journal of Medicine.
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Targeting Immune Cells to Improve Long-Term Survival in Organ Transplantation
Northwestern Medicine scientists have discovered how a subset of immune cells are essential for successful organ transplantation acceptance, according to a recent study published in The Journal of Clinical Investigation.
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Innate Immune ‘Mismatch’ Could Transform Kidney Transplant Outcomes
A genetic mismatch may influence kidney transplant success and could inform how donor-recipient compatibility is assessed, according to a study published in Science Translational Medicine.
