Tag: Research
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Pioneering New Techniques in the Fight Against Alzheimer’s Disease
More than seven million Americans aged 65 years and older currently live with Alzheimer’s disease, according to recent estimates from the Alzheimer’s Association. As the prevalence of the disease increases, so does the need for research that identifies underlying mechanisms of disease to enhance the effectiveness of current therapies and inform new therapeutic strategies.
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New Biomarkers Needed to Evaluate Heart Failure Risk Post-Pregnancy
Biomarkers used to predict heart failure risk in the general population may be ineffective for assessing risk after pregnancies complicated by hypertension or diabetes, according to a study published in JAMA Cardiology.
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The Antibiotic That Takes the Bite Out of Lyme
A new Northwestern study shows piperacillin, an antibiotic, effectively cured mice of Lyme disease at a dose 100 times smaller than the effective dose of doxycycline, the current gold-standard treatment.
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Post-Treatment Lyme Disease Syndrome May Be Driven by Remnants of Infection
A new Northwestern study may explain why the body may continue to respond to an invisible threat long after bacterial death in Lyme disease.
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Novel Mechanisms Help Lethal Bacteria Recognize and Infect Cells
Scientists led by Karla Satchell, PhD, have discovered previously unknown molecular mechanisms that help a type of foodborne bacteria called Vibrio vulnificus recognize host cells and initiate infection, according to a recent study published in Science Advances.
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Novel Mechanisms Regulate Immune Response to Cancer and Infection
Northwestern Medicine investigators have discovered new intracellular mechanisms that help specialized immune cells adapt and respond to disease and acute inflammation, findings that may inform the development of targeted therapies for cancer and tissue injury, according to a recent study published in the Journal of Clinical Investigation.
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Regenerating Eyedrops May Help Damaged Corneas Heal
Northwestern Medicine investigators have developed first-of-its-kind eyedrops that use synthetic nanoparticles to help the eye regenerate cells that have been damaged by mustard keratopathy, or exposure to mustard gas, and other inflammatory eye diseases, detailed in a recent study published in the journal NPJ Regenerative Medicine.
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Common Genetic Variants Help Determine Heart Failure Risk, Study Finds
Screening for common genetic variants in addition to rare genetic variants can help improve patient risk stratification for heart failure, according to a recent Northwestern Medicine study published in Nature Genetics.
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Distinguished Molecular Biologist Delivers 2025 Kimberly Prize Lecture
Esteemed molecular biologist Ron Evans, PhD, known for his groundbreaking discovery of the nuclear receptor superfamily, delivered the third Kimberly Prize in Biochemistry and Molecular Genetics Lecture to a crowded auditorium of Feinberg faculty, staff, fellows and students on April 30.
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Enzyme Drives Treatment Resistance in Ovarian Cancer
Northwestern Medicine scientists have identified a key driver of chemotherapy resistance in advanced ovarian cancer, according to a study published in the Journal of Clinical Investigation.
