Tag: Pathology
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Cells ‘Switch’ on Protein Factories After Injury, Study Finds
Scientists have uncovered a novel mechanism through which skin cells organize and control protein production during homeostasis and wound healing, according to a new study published in Developmental Cell.
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Transcription Factors Form Continuous ‘Circuit’ That Regulates T-cell Exhaustion
Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic strategies for managing infections and cancer, according to a recent Northwestern Medicine study.
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Uncovering a Genetic Driver of Rare Early-Onset Dementia
A global team of scientists has uncovered a new genetic risk factor for a rare and aggressive form of early-onset dementia, according to a study published in Nature Genetics.
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Novel Biomarker May Predict Immunotherapy Resistance
Northwestern Medicine scientists have identified a novel biomarker for immune immunotherapy resistance in cancer that may also serve as a potential therapeutic target for patients who don’t respond well to immunotherapy, according to a recent study published in The Journal of Clinical Investigation.
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Molecular Mechanisms Support Long-term Immunity
Scientists in the laboratory of Weiguo Cui, PhD, have identified novel molecular mechanisms that help specialized T-cells maintain long-term immunity in response to chronic infection and cancer, according to recent findings published in Nature Immunology.
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How a ‘DNA Detangler’ Gene Protects Against Blood Cancer
A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that may lead to leukemia, according to findings published in Nature Communications.
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Targeting Immune Cells to Improve Long-Term Survival in Organ Transplantation
Northwestern Medicine scientists have discovered how a subset of immune cells are essential for successful organ transplantation acceptance, according to a recent study published in The Journal of Clinical Investigation.
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How a Common Metabolite Worsens Inflammatory Bowel Disease
Northwestern Medicine investigators have identified a surprising culprit in the progression of inflammatory bowel disease, according to a study published in Nature Immunology.
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Study Establishes Cell Death as a Driving Force in Glioblastoma
Cell death has been found to be a driving factor in glioblastoma progression, according to a Northwestern-Medicine-led study published in the Proceedings of the National Academy of Sciences.
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Using AI To Analyze Placentas for Faster Detection of Neonatal, Maternal Problems
New research from scientists at Northwestern Medicine and Penn State describes PlacentaVision, a computer program that can analyze a simple photograph of the placenta to detect abnormalities associated with infection and neonatal sepsis.
