Tag: Neurology and Neuroscience
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Iron Accumulation Linked with Age-Related Cognitive Decline
Age-related breakdowns in regulatory mechanisms cause iron to build up in the brain, increasing oxidative stress and causing cellular damage, according to a recent Northwestern Medicine study.
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Improving Pre-Surgical Workups for Epilepsy
Using MRI, EEG and clinical characteristics, the pre-surgical workup can predict if patients with epilepsy will benefit from a more invasive examination.
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New Autism Biomarker Discovered in Cerebrospinal Fluid
Northwestern Medicine scientists have discovered a biomarker for one type of autism within cerebrospinal fluid, according to a recent study.
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Uncovering the Degenerative Basis of Parkinson’s Disease
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.
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Fatty Acid Length Predicts Parkinson’s Disease Risk
Long chains of fatty acids in the lysosome are associated with a degenerative form of Gaucher disease, an inherited condition related to Parkinson’s disease.
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ALS Therapy Should Target Brain, Not Just Spine
A new study has shown that the degeneration of brain motor neurons in ALS is not merely a byproduct of the spinal motor neuron degeneration, and is a target for future treatments for the disease.
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Combination Therapy Reduces Toxic Aggregates in Parkinson’s Disease
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
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Neurobiologists Identify a New Gene Important for Healthy Daily Rhythms
A recent study identified a gene that is critical for daily behavioral rhythms, involved in a molecular pathway by which the core circadian clock controls daily sleep-wake cycles.
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‘Dancing Molecules’ Successfully Repair Severe Spinal Cord Injuries
A new injectable therapy harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries, allowing animal subjects to regain the ability to walk.
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New Insights into the Mechanism of ALS
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
