Tag: Neurology and Neuroscience
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ALS Therapy Should Target Brain, Not Just Spine
A new study has shown that the degeneration of brain motor neurons in ALS is not merely a byproduct of the spinal motor neuron degeneration, and is a target for future treatments for the disease.
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Combination Therapy Reduces Toxic Aggregates in Parkinson’s Disease
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
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Neurobiologists Identify a New Gene Important for Healthy Daily Rhythms
A recent study identified a gene that is critical for daily behavioral rhythms, involved in a molecular pathway by which the core circadian clock controls daily sleep-wake cycles.
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‘Dancing Molecules’ Successfully Repair Severe Spinal Cord Injuries
A new injectable therapy harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries, allowing animal subjects to regain the ability to walk.
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New Insights into the Mechanism of ALS
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
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A New Way to Improve Skilled Movements Via Sleep
The ability to learn novel physical movements, similar to those taught in rehabilitation for people with stroke, can be improved by reactivating specific memories of the new task during sleep, according to a new study.
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Gene Therapy Boosts Parkinson’s Disease Drug Benefits
A new Northwestern Medicine study published in Nature explains why dopamine neurons are lost in Parkinson’s disease, and demonstrated that a gene therapy targeting the brain’s substantia nigra can substantially boost the benefits of levodopa, an important medication for treating the disease.
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$18 Million For Parkinson’s Disease Research to Study Brain Circuits Driving Symptoms
Northwestern University scientists have received two awards totaling nearly $18 million to address key knowledge gaps in the basic circuit mechanisms that contribute to the development and progression of Parkinson’s disease.
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Lewy Body Dementia Exacerbated by Immune Response
T-cells respond to buildup of alpha-synuclein with a harmful auto-immune response, according to a Northwestern Medicine study published in Science.
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The Long Haul
The growing number of patients suffering from long-term complications of COVID-19 has spurred the creation of Northwestern Medicine’s Comprehensive COVID-19 Center, which provides coordinated, multidisciplinary care.
