
An experimental drug designed to silence a gene strongly linked to Parkinson’s disease has shown encouraging effects in a first-in-human clinical trial, according to a study published in Nature Medicine.

A new Northwestern University study suggests that higher‑level brain systems that interpret and organize perception may play a central role in imagination in addition to sensory systems.

A new Northwestern study in humans and mice has discovered a novel biomarker of schizophrenia that could also serve as a new drug candidate to treat the cognitive symptoms of the disorder.

A first‑ever gene‑regulation therapy tested in early‑phase clinical trials co‑led by Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago has proven safe in children with Dravet syndrome who have exhausted conventional treatment options, according to a study published in the New England Journal of Medicine.

New research shows that the brains of “SuperAgers” continue to generate new neurons in the hippocampus at levels far higher than typical older adults, and even much younger individuals.

A team led by Northwestern University and Shirley Ryan AbilityLab scientists have developed a new technology that can eavesdrop on the hidden electrical dialogues unfolding inside miniature, lab-grown human brain-like tissues.

Using lab-grown human spinal cord organoids — miniature organs derived from stem cells — Northwestern scientists have modeled different types of spinal cord injuries and tested a promising new regenerative therapy.

Patients with long COVID-19 in the U.S. report far higher rates of brain fog, depression and cognitive symptoms than patients in countries such as India and Nigeria, according to a large international study led by Northwestern Medicine.

Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein accumulation in neurodegenerative diseases, according to a study published in Nature Communications.

A Northwestern Medicine study has uncovered a promising new therapeutic approach for a rare genetic brain disorder, according to findings published in Nature Communications.